Empathy and schizotypy following acquired brain damage.

OBJECTIVES: Acquired brain damage is associated with a reduced capacity for empathy, and emerging evidence indicates that there may also be elevated levels of schizotypy. However, although a relationship between schizotypy and empathy has been identified in other populations, no study to date has tested whether this relationship is also evident following acquired brain damage, and if so, whether it is specific to certain types of brain damage, or specific types of empathy. METHODS: People with acquired brain damage restricted to either frontal (N = 18) or non-frontal (N = 24) neural structures and demographically matched controls (N = 48) completed an assessment of schizotypy and a measure of empathy that differentiated between cognitive, emotional, and social skills empathy. RESULTS: Relative to the control group, people with frontal and non-frontal brain injuries reported elevated schizotypy, with the frontal group also reporting lower social skills empathy. Only in the frontal group was there support for an association between schizotypy and empathy, and this was specific to the social skills component of empathy. CONCLUSIONS: Schizotypy levels are elevated following brain damage, and frontal brain injury is linked to greater difficulties with the social skills component of empathy. Schizotypy appears to be an important consideration when understanding the link between empathy and frontal brain damage, with higher schizotypy levels associated with reduced social skills empathy in this population. Future research is now needed to establish whether problems with more implicit aspects of social understanding are relevant to understanding the relationship between schizotypy and poor social behavioural outcomes identified in other clinical groups that present with frontal brain damage. PRACTITIONER POINTS: People with an acquired brain injury experience deficits in empathic processing as well as elevated levels of schizotypal traits. Schizotypy levels and social skills empathy were inversely related in people who had experienced a frontal acquired brain injury, suggesting that schizotypy might be important for understanding social skill difficulties in this particular population. These findings highlight the potential benefit of including social cognitive assessments and schizotypy measures in standard neuropsychological assessment batteries.

Developing a Computerized Brief Cognitive Screening Battery for Botswana: A Feasibility Study.

OBJECTIVE: To determine the feasibility of using a brief computerized battery for assessing cognition in citizens of Botswana. METHOD: A group of 134 healthy subjects were administered a brief computerized battery of tests (Stroop, Symbol Digit Modalities Test (c-SDMT), and 2 and 4 second versions of the Paced Visual Serial Addition Test (PVSAT)). Half the subjects were tested in English and the other half in Setswana. RESULTS: All subjects completed the 20 min battery. Participants administered the tests in English had more years of education (p < .001) and were more likely to be male (p = .024) than those administered the tests in Setswana. There were no significant cognitive differences between the English and Setswana groups. Predictors of cognition were education (c-SDMT, PVSAT 4 and 2 second versions), age (Stroop, c-SDMT), and sex (c-SDMT), with females performing better than males on the latter. Language was not associated with performance on any of the cognitive tests and there were no significant interactions between language and any of the demographic predictors of cognition. CONCLUSIONS: The results demonstrate that our brief computerized approach is feasible with similar findings obtained for both language groups. Two further phases to the development of the Botswana version of the brief computerized battery can now proceed. The first is to obtain normative data from a larger sample representative of Botswana society in general. The second will be to validate the cognitive measures in a sample of people with acquired brain injury using the normative data to determine thresholds for impairment.