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3.
BMJ Case Rep ; 12(9)2019 Sep 11.
Artigo em Inglês | MEDLINE | ID: mdl-31511270

RESUMO

A 29-year-old woman with recurrent pelvic pain that progressed post partum was diagnosed with a multicystic pararectal lesion on ultrasound and CT scan. Physiology was conducted to establish a preoperative function and pudendal nerve integrity. The lesion was resected using a Da Vinci Xi robotic system. She recovered uneventfully with complete resolution of her symptoms. Hindgut cysts most often arise in the presacral space as the result of incomplete embryogenesis. Patients may present with various non-specific symptoms. Although the majority are benign, resection is recommended, as there is a 30%-43% risk of malignancy.


Assuntos
Cistos/cirurgia , Hamartoma/cirurgia , Procedimentos Cirúrgicos Robóticos , Adulto , Cistos/diagnóstico por imagem , Feminino , Hamartoma/diagnóstico por imagem , Humanos , Reto , Região Sacrococcígea , Vagina
6.
Acta Otolaryngol ; 125(4): 422-5, 2005 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15823815

RESUMO

CONCLUSIONS: Despite having very high neuronal firing rates, the VNC does not have unusually high mitochondrial activity in vitro. This study is the first in which functionally active mitochondria from the hindbrain have been isolated and characterized. OBJECTIVE: Neurons in the vestibular nucleus complex (VNC) have exceptionally high spontaneous firing rates. Neuronal mitochondria generate adenosine triphosphate critical for maintaining the membrane potentials required for axon firing. We therefore hypothesized a high rate of mitochondrial activity in the VNC. MATERIAL AND METHODS: To test this hypothesis, we compared mitochondrial activity in the VNC with mitochondrial activity from another area of the hindbrain, the cerebellum. Mitochondrial respiratory activity was assessed by measuring oxidative phosphorylation and mitochondrial respiratory enzyme complex activity. RESULTS: Assay results were not significantly different in the VNC compared to those obtained with the cerebellum or with rat brain mitochondria in previous studies.


Assuntos
Transporte de Elétrons/fisiologia , Mitocôndrias/fisiologia , Núcleos Vestibulares/fisiologia , Trifosfato de Adenosina/metabolismo , Animais , Células Cultivadas , Cerebelo/fisiologia , Citrato (si)-Sintase/metabolismo , Complexo I de Transporte de Elétrons/metabolismo , Complexo II de Transporte de Elétrons/metabolismo , Complexo III da Cadeia de Transporte de Elétrons/metabolismo , Complexo IV da Cadeia de Transporte de Elétrons/metabolismo , Masculino , Potenciais da Membrana/fisiologia , Neurônios/fisiologia , Fosforilação Oxidativa , Ratos , Ratos Wistar
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