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1.
Sci Rep ; 14(1): 2434, 2024 01 29.
Artigo em Inglês | MEDLINE | ID: mdl-38287062

RESUMO

The increase in eye disorders among older individuals has raised concerns, necessitating early detection through regular eye examinations. Age-related macular degeneration (AMD), a prevalent condition in individuals over 45, is a leading cause of vision impairment in the elderly. This paper presents a comprehensive computer-aided diagnosis (CAD) framework to categorize fundus images into geographic atrophy (GA), intermediate AMD, normal, and wet AMD categories. This is crucial for early detection and precise diagnosis of age-related macular degeneration (AMD), enabling timely intervention and personalized treatment strategies. We have developed a novel system that extracts both local and global appearance markers from fundus images. These markers are obtained from the entire retina and iso-regions aligned with the optical disc. Applying weighted majority voting on the best classifiers improves performance, resulting in an accuracy of 96.85%, sensitivity of 93.72%, specificity of 97.89%, precision of 93.86%, F1 of 93.72%, ROC of 95.85%, balanced accuracy of 95.81%, and weighted sum of 95.38%. This system not only achieves high accuracy but also provides a detailed assessment of the severity of each retinal region. This approach ensures that the final diagnosis aligns with the physician's understanding of AMD, aiding them in ongoing treatment and follow-up for AMD patients.


Assuntos
Atrofia Geográfica , Degeneração Macular Exsudativa , Humanos , Idoso , Fundo de Olho , Retina , Degeneração Macular Exsudativa/diagnóstico , Atrofia Geográfica/diagnóstico por imagem , Aprendizado de Máquina
2.
J Supercomput ; : 1-38, 2023 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-37359324

RESUMO

In the last decade, the need for a non-contact biometric model for recognizing candidates has increased, especially after the pandemic of COVID-19 appeared and spread worldwide. This paper presents a novel deep convolutional neural network (CNN) model that guarantees quick, safe, and precise human authentication via their poses and walking style. The concatenated fusion between the proposed CNN and a fully connected model has been formulated, utilized, and tested. The proposed CNN extracts the human features from two main sources: (1) human silhouette images according to model-free and (2) human joints, limbs, and static joint distances according to a model-based via a novel, fully connected deep-layer structure. The most commonly used dataset, CASIA gait families, has been utilized and tested. Numerous performance metrics have been evaluated to measure the system quality, including accuracy, specificity, sensitivity, false negative rate, and training time. Experimental results reveal that the proposed model can enhance recognition performance in a superior manner compared with the latest state-of-the-art studies. Moreover, the suggested system introduces a robust real-time authentication with any covariate conditions, scoring 99.8% and 99.6% accuracy in identifying casia (B) and casia (A) datasets, respectively.

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