Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Environ Sci Pollut Res Int ; 26(14): 14184-14193, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30859440

RESUMO

Acrylamide (ACR) is a widespread industrial chemical with recognized adverse effects not only to humans but to other organisms in the environment as well. In the present study, the ecotoxicological effects of dietary exposure to sublethal concentration (1/20 LC50) of ACR on the land snail, Theba pisana after 2 weeks of exposure and 1-week recovery with respect to oxidative stress parameters; lipid peroxidation (LPO), reduced glutathione (GSH), catalase (CAT), and glutathione-S-transferase (GST), cytogenetic parameter; deoxyribonucleic acid (DNA) content, as well as immunological parameters; cell death, phagocytosis, lysosomal membrane stability (LMS), lectins, superoxide anion (O2-) generation, phenoloxidase (PO), peroxidase (POD), and hemocyanin (Hc) were examined. The results showed that ACR significantly increased LPO level and the activity of CAT and GST, cell death, and Hc level, whereas a significant decline in DNA and GSH contents, phagocytic activity, LMS, lectins, O2- generation, POD, and PO activities compared to the controls after 2-week exposure was observed. After 1-week recovery, most of the tested parameters in exposed snails were permanent and not reversible to the control levels. This study suggests that the tested multiple parameters of T. pisana species may be used as biomarkers of ACR exposure. Besides, T. pisana snails could be used as a good sentinel organism for ACR exposure in pollution monitoring studies.


Assuntos
Acrilamida/toxicidade , Poluentes Ambientais/toxicidade , Caramujos/fisiologia , Acrilamida/metabolismo , Animais , Biomarcadores/metabolismo , Catalase/metabolismo , Ecotoxicologia , Glutationa/metabolismo , Glutationa Peroxidase/metabolismo , Glutationa Transferase/metabolismo , Dose Letal Mediana , Peroxidação de Lipídeos/efeitos dos fármacos , Estresse Oxidativo/efeitos dos fármacos , Caramujos/efeitos dos fármacos
2.
Environ Sci Pollut Res Int ; 26(7): 6922-6930, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30644046

RESUMO

In the current study, the toxicity bioassay of three pollutants abamectin (ABM), thiamethoxam (TMX), and acrylamide (ACR) against land snails Theba pisana was measured. Also, the ecotoxicological effects of dietary exposure to sublethal concentration (1/20 LC50) of these pollutants for 2-week exposure and 1-week recovery on some physiological endpoints evaluated as feeding activity, growth response, and carbonic anhydrase activity as a marker in charge of shell formation and seromucoid level as a marker in charge of mucus synthesis of the snails were studied. The results exhibited that the 48-h LC50 values were 0.91, 313.8, and 45.7 µg/g dry food for ABM, TMX, and ACR, respectively. The sublethal concentrations of these pollutants in the diet after 2-week exposure were found to reduce the food consumption and inhibit growth rate of the snails. Also, the data illustrated that carbonic anhydrase activity was significantly decreased. On the other hand, there was a significant increase in the seromucoid level as a marker responsible for mucus synthesis in ABM- and TMX-exposed snails, while ACR showed significantly decreased level when compared to control. After 1-week recovery, the tested endpoints of treated snails were slightly repaired but still less than that of the untreated animals. The overall outcome of this investigation suggests the utility of this animal as a good bioindicator organism for ABM, TMX, and ACR exposure in pollution monitoring studies.


Assuntos
Monitoramento Ambiental/métodos , Caramujos/fisiologia , Animais , Biomarcadores/metabolismo , Ecotoxicologia , Poluentes Ambientais/metabolismo , Poluentes Ambientais/toxicidade , Poluentes do Solo/metabolismo , Poluentes do Solo/toxicidade
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...