[Clinical and immunological features of concomitant HIV/tuberculosis infection and HIV infection without tuberculosis].

The clinical and hematological manifestations and functional state of the immune system were comparatively evaluated in patients with concomitant HIV/tuberculosis (TB) infection (n = 84) and in those with HIV infection without tuberculosis (n = 106). The course of concomitant HIV-TB infection was ascertained to differ from HIV monoinfection in a diversity of additional exposures that aggravated the patients' general condition. These included: the parameters of a long proceeding inflammatory process, which were accompanied by the signs of the infection-toxic syndrome, inflammatory changes in the hemogram, by a sharp stimulation of the nonspecific link of immunity. So the comparative analysis of the trend in HIV infection in combination with active tuberculosis and HIV monoinfection revealed a prompter progression of the disease in the former case.

[Clinical and immunological features of the course of tuberculosis concurrent with HIV infection].

The clinical and immunological features of the course of tuberculosis concurrent with HIV infection were studied in 109 patients. Thirty-eight patients were found to have active tuberculosis to HIV infection; 22 patients were diagnosed to have HIV infection and tuberculosis, and 49 patients developed tuberculosis in the presence of HIV infection. The most acute course of the disease with severe infection-toxic and asthenovegetative syndromes was observed in patients with simultaneous detection of HIV infection and tuberculosis, and, when tuberculosis joins as a secondary disease in the presence of HIV infection, the bronchopulmonary syndrome, body weight loss, lymphoadenopathy, and skin lesion were pronounced at most. The most severe clinical forms of tuberculosis were observed in a group where tuberculosis manifested itself as an opportunistic disease in the presence of moderate and severe immunodeficiency.