Classification of cancer types based on microRNA expression using a hybrid radial basis function and particle swarm optimization algorithm.

The diagnosis and treatment of cancer is one of the most challenging aspects of the medical profession, despite advances in disease diagnosis. MicroRNAs are small noncoding RNA molecules involved in regulating gene expression and are associated with several cancer types. Therefore, the analysis of microRNA data has become one of the most important areas of cancer research in recent years. This paper presents an improved method for cancer-type classification based on microRNA expression data using a hybrid radial basis function (RBF) and particle swarm optimization (PSO) algorithm. Two datasets containing microRNA information were used, and preprocessing and normalization operations were performed on the raw data. Feature selection was carried out by using the PSO algorithm, which can identify the most relevant and informative features in the data along with helping to prioritize them. Using a PSO algorithm for feature selection is an effective approach to microRNA analysis. This enhances the accuracy and reliability of cancer-type classifications based on microRNA expression data. In the proposed method, we, respectively, achieved an accuracy of 0.95% and 0.91% on both datasets, with an average of 0.93%, using an improved RBF neural network classifier. These results demonstrate that the proposed method outperforms previous works. RESEARCH HIGHLIGHTS: To enhance the accuracy of cancer-type classifications based on microRNA expression data. We present a minimal feature selection method using particle swarm optimization to reduce computational load & radial basis function to improve accuracy.

Identification of Anomalies in Mammograms through Internet of Medical Things (IoMT) Diagnosis System.

Breast cancer is the primary health issue that women may face at some point in their lifetime. This may lead to death in severe cases. A mammography procedure is used for finding suspicious masses in the breast. Teleradiology is employed for online treatment and diagnostics processes due to the unavailability and shortage of trained radiologists in backward and remote areas. The availability of online radiologists is uncertain due to inadequate network coverage in rural areas. In such circumstances, the Computer-Aided Diagnosis (CAD) framework is useful for identifying breast abnormalities without expert radiologists. This research presents a decision-making system based on IoMT (Internet of Medical Things) to identify breast anomalies. The proposed technique encompasses the region growing algorithm to segment tumor that extracts suspicious part. Then, texture and shape-based features are employed to characterize breast lesions. The extracted features include first and second-order statistics, center-symmetric local binary pattern (CS-LBP), a histogram of oriented gradients (HOG), and shape-based techniques used to obtain various features from the mammograms. Finally, a fusion of machine learning algorithms including K-Nearest Neighbor (KNN), Support Vector Machine (SVM), and Linear Discriminant Analysis (LDA are employed to classify breast cancer using composite feature vectors. The experimental results exhibit the proposed framework's efficacy that separates the cancerous lesions from the benign ones using 10-fold cross-validations. The accuracy, sensitivity, and specificity attained are 96.3%, 94.1%, and 98.2%, respectively, through shape-based features from the MIAS database. Finally, this research contributes a model with the ability for earlier and improved accuracy of breast tumor detection.

Arabic Speech Analysis for Classification and Prediction of Mental Illness due to Depression Using Deep Learning.

Depression is a global prevalent ailment for possible mental illness or mental disorder globally. Recognizing depressed early signs is critical for evaluating and preventing mental illness. With the progress of machine learning, it is possible to make intelligent systems capable of detecting depressive symptoms using speech analysis. This study presents a hybrid model to identify and predict mental illness from Arabic speech analysis due to depression. The proposed hybrid model comprises convolutional neural network (CNN) and a support vector machine (SVM) to identify and predict mental disorders. Experiments are performed on the Arabic speech benchmark data set of 200 speeches. A total of 70% of data were reserved for training, while 30% of data were to test the proposed model. The hybrid model (CNN + SVM) attained a 90.0% and 91.60% accuracy rate to predict the depression from Arabic speech analysis for training and testing stages. To authenticate the results of a proposed hybrid model, recurrent neural network (RNN) and CNN are also applied to the same data set individually, and the results are compared with each other. The RNN achieved an 80.70% and 81.60% accuracy rate to predict depression while speaking in the training and testing stages. The CNN predicted the depression in the training and testing stages with 88.50% and 86.60% accuracy rates. Based on the analysis, the proposed hybrid model secured better prediction results than individual RNN and CNN models on the same data set. Furthermore, the suggested model had a lower FPR, FNR, and higher accuracy, AUC, sensitivity, and specificity rate than individual RNN, CNN model performance in predicting depression. Finally, the achieved findings will be helpful to classify depression while speaking Arabic/speech and will be beneficial for physicians, psychiatrists, and psychologists in the detection of depression.

Microscopic handcrafted features selection from computed tomography scans for early stage lungs cancer diagnosis using hybrid classifiers.

Lung's cancer is the leading cause of cancer-related deaths worldwide. Recently cancer mortality rate and incidence increased exponentially. Many patients with lung cancer are diagnosed late, so the survival rate is shallow. Machine learning approaches have been widely used to increase the effectiveness of cancer detection at an early stage. Even while these methods are efficient in detecting specific forms of cancer, there is no known technique that could be used universally and consistently to identify new malignancies. As a result, cancer diagnosis via machine learning algorithms is still fresh area of research. Computed tomography (CT) images are frequently employed for early cancer detection and diagnosis because they contain significant information. In this research, an automated lung cancer detection and classification framework is proposed which consists of preprocessing, three patches local binary pattern feature encoding, local binary pattern, histogram of oriented gradients features are extracted and fused. The fast learning network (FLN) is a novel machine-learning technique that is fast to train and economical in terms of processing resources. However, the FLN's internal power parameters (weight and basis) are randomly initialized, resulting it an unstable algorithm. Therefore, to enhance accuracy, FLN is hybrid with K-nearest neighbors to classify texture and appearance-based features of lung chest CT scans from Kaggle dataset into cancerous and non-cancerous images. The proposed model performance is evaluated using accuracy, sensitivity, specificity on the Kaggle benchmark dataset that is found comparable in state of the art using simple machine learning strategies. RESEARCH HIGHLIGHTS: Fast learning network and K-nearest neighbor hybrid classifier proposed first time for lung cancer classification using handcrafted features including three patches local binary pattern, local binary pattern, and histogram of oriented gradients. Promising results obtained from novel simple combination.

Breast microscopic cancer segmentation and classification using unique 4-qubit-quantum model.

The visual inspection of histopathological samples is the benchmark for detecting breast cancer, but a strenuous and complicated process takes a long time of the pathologist practice. Deep learning models have shown excellent outcomes in clinical diagnosis and image processing and advances in various fields, including drug development, frequency simulation, and optimization techniques. However, the resemblance of histopathologic images of breast cancer and the inclusion of stable and infected tissues in different areas make detecting and classifying tumors on entire slide images more difficult. In breast cancer, a correct diagnosis is needed for complete care in a limited amount of time. An effective detection can relieve the pathologist's workload and mitigate diagnostic subjectivity. Therefore, this research work investigates improved the pre-trained xception and deeplabv3+ design semantic model. The model has been trained on input images with ground masks on the tuned parameters that significantly improve the segmentation of ultrasound breast images into respective classes, that is, benign/malignant. The segmentation model delivered an accuracy of greater than 99% to prove the model's effectiveness. The segmented images and histopathological breast images are transferred to the 4-qubit-quantum circuit with six-layered architecture to detect breast malignancy. The proposed framework achieved remarkable performance as contrasted to currently published methodologies. HIGHLIGHTS: This research proposed hybrid semantic model using pre-trained xception and deeplabv3 for breast microscopic cancer classification in to benign and malignant classes at accuracy of 95% accuracy, 99% accuracy for detection of breast malignancy.

Optimizing the transfer-learning with pretrained deep convolutional neural networks for first stage breast tumor diagnosis using breast ultrasound visual images.

Female accounts for approximately 50% of the total population worldwide and many of them had breast cancer. Computer-aided diagnosis frameworks could reduce the number of needless biopsies and the workload of radiologists. This research aims to detect benign and malignant tumors automatically using breast ultrasound (BUS) images. Accordingly, two pretrained deep convolutional neural network (CNN) models were employed for transfer learning using BUS images like AlexNet and DenseNet201. A total of 697 BUS images containing benign and malignant tumors are preprocessed and performed classification tasks using the transfer learning-based CNN models. The classification accuracy of the benign and malignant tasks is completed and achieved 92.8% accuracy using the DensNet201 model. The results thus achieved compared in state of the art using benchmark data set and concluded proposed model outperforms in accuracy from first stage breast tumor diagnosis. Finally, the proposed model could help radiologists diagnose benign and malignant tumors swiftly by screening suspected patients.

Authentication through gender classification from iris images using support vector machine.

Soft biometric information, such as gender, iris, and voice, can be helpful in various applications, such as security, authentication, and validation. Iris is secure biometrics with low forgery and error rates due to its highly certain features are being used in the last few decades. Iris recognition could be used both independently and in part for secure recognition and authentication systems. Existing iris-based gender classification techniques have low accuracy rates as well as high computational complexity. Accordingly, this paper presents an authentication approach through gender classification from iris images using support vector machine (SVM) that has an excellent response to sustained changes using the Zernike, Legendre invariant moments, and Gradient-oriented histogram. In this study, invariant moments are used as feature extraction from iris images. After extracting these descriptors' attributes, the attributes are categorized through keycode fusion. SVM is employed for gender classification using a fused feature vector. The proposed approach is evaluated on the CVBL data set and results are compared in state of the art based on local binary patterns and Gabor filters. The proposed approach came out with 98% gender classification rate with low computational complexity that could be used as an authentication measure.

Internet of medical things embedding deep learning with data augmentation for mammogram density classification.

Females are approximately half of the total population worldwide, and most of them are victims of breast cancer (BC). Computer-aided diagnosis (CAD) frameworks can help radiologists to find breast density (BD), which further helps in BC detection precisely. This research detects BD automatically using mammogram images based on Internet of Medical Things (IoMT) supported devices. Two pretrained deep convolutional neural network models called DenseNet201 and ResNet50 were applied through a transfer learning approach. A total of 322 mammogram images containing 106 fatty, 112 dense, and 104 glandular cases were obtained from the Mammogram Image Analysis Society dataset. The pruning out irrelevant regions and enhancing target regions is performed in preprocessing. The overall classification accuracy of the BD task is performed and accomplished 90.47% through DensNet201 model. Such a framework is beneficial in identifying BD more rapidly to assist radiologists and patients without delay.

Brain tumor segmentation using K-means clustering and deep learning with synthetic data augmentation for classification.

Image processing plays a major role in neurologists' clinical diagnosis in the medical field. Several types of imagery are used for diagnostics, tumor segmentation, and classification. Magnetic resonance imaging (MRI) is favored among all modalities due to its noninvasive nature and better representation of internal tumor information. Indeed, early diagnosis may increase the chances of being lifesaving. However, the manual dissection and classification of brain tumors based on MRI is vulnerable to error, time-consuming, and formidable task. Consequently, this article presents a deep learning approach to classify brain tumors using an MRI data analysis to assist practitioners. The recommended method comprises three main phases: preprocessing, brain tumor segmentation using k-means clustering, and finally, classify tumors into their respective categories (benign/malignant) using MRI data through a finetuned VGG19 (i.e., 19 layered Visual Geometric Group) model. Moreover, for better classification accuracy, the synthetic data augmentation concept i s introduced to increase available data size for classifier training. The proposed approach was evaluated on BraTS 2015 benchmarks data sets through rigorous experiments. The results endorse the effectiveness of the proposed strategy and it achieved better accuracy compared to the previously reported state of the art techniques.

Machine learning techniques to detect and forecast the daily total COVID-19 infected and deaths cases under different lockdown types.

COVID-19 has impacted the world in many ways, including loss of lives, economic downturn and social isolation. COVID-19 was emerged due to the SARS-CoV-2 that is highly infectious pandemic. Every country tried to control the COVID-19 spread by imposing different types of lockdowns. Therefore, there is an urgent need to forecast the daily confirmed infected cases and deaths in different types of lockdown to select the most appropriate lockdown strategies to control the intensity of this pandemic and reduce the burden in hospitals. Currently are imposed three types of lockdown (partial, herd, complete) in different countries. In this study, three countries from every type of lockdown were studied by applying time-series and machine learning models, named as random forests, K-nearest neighbors, SVM, decision trees (DTs), polynomial regression, Holt winter, ARIMA, and SARIMA to forecast daily confirm infected cases and deaths due to COVID-19. The models' accuracy and effectiveness were evaluated by error based on three performance criteria. Actually, a single forecasting model could not capture all data sets' trends due to the varying nature of data sets and lockdown types. Three top-ranked models were used to predict the confirmed infected cases and deaths, the outperformed models were also adopted for the out-of-sample prediction and obtained very close results to the actual values of cumulative infected cases and deaths due to COVID-19. This study has proposed the auspicious models for forecasting and the best lockdown strategy to mitigate the causalities of COVID-19.