Novel Second-Order Fully Differential All-Pass Filter Using CNTFETs.

In this paper, a new carbon nanotube field effect transistor (CNTFET)-based second-order fully differential all-pass filter circuit is presented. The realized filter uses CNTFET-based transconductors and grounded capacitors. An active-only second-order fully differential all-pass filter circuit topology is also presented by replacing the grounded capacitance with a CNTFET-based varactor to achieve filter tunability. By controlling the varactor capacitance, active-only second-order fully differential all-pass filter tunability in the range of 15 GHz to 27.5 GHz is achieved. The proposed active-only circuit works on -oltage, low-power dissipation and high tunable pole frequency. The realized circuit operations are verified through the HPSPICE simulation tool. Deng's CNTFET model is utilized to verify the filter performances at the 16 nm technology node. It is seen that the proposed filter simulation justifies the theoretical predictions and works efficiently in the deep-submicron technology.

Efficacy of a Single-Dose, Inactivated Oral Cholera Vaccine in Bangladesh.

BACKGROUND: A single-dose regimen of the current killed oral cholera vaccines that have been prequalified by the World Health Organization would make them more attractive for use against endemic and epidemic cholera. We conducted an efficacy trial of a single dose of the killed oral cholera vaccine Shanchol, which is currently given in a two-dose schedule, in an urban area in which cholera is highly endemic. METHODS: Nonpregnant residents of Dhaka, Bangladesh, who were 1 year of age or older were randomly assigned to receive a single dose of oral cholera vaccine or oral placebo. The primary outcome was vaccine protective efficacy against culture-confirmed cholera occurring 7 to 180 days after dosing. Prespecified secondary outcomes included protective efficacy against severely dehydrating culture-confirmed cholera during the same interval, against cholera and severe cholera occurring 7 to 90 versus 91 to 180 days after dosing, and against cholera and severe cholera according to age at baseline. RESULTS: A total of 101 episodes of cholera, 37 associated with severe dehydration, were detected among the 204,700 persons who received one dose of vaccine or placebo. The vaccine protective efficacy was 40% (95% confidence interval [CI], 11 to 60%; 0.37 cases per 1000 vaccine recipients vs. 0.62 cases per 1000 placebo recipients) against all cholera episodes, 63% (95% CI, 24 to 82%; 0.10 vs. 0.26 cases per 1000 recipients) against severely dehydrating cholera episodes, and 63% (95% CI, -39 to 90%), 56% (95% CI, 16 to 77%), and 16% (95% CI, -49% to 53%) against all cholera episodes among persons vaccinated at the age of 5 to 14 years, 15 or more years, and 1 to 4 years, respectively, although the differences according to age were not significant (P=0.25). Adverse events occurred at similar frequencies in the two groups. CONCLUSIONS: A single dose of the oral cholera vaccine was efficacious in older children (≥5 years of age) and in adults in a setting with a high level of cholera endemicity. (Funded by the Bill and Melinda Gates Foundation and others; ClinicalTrials.gov number, NCT02027207.).

Strategies for providing healthcare services to street-dwellers in Dhaka city: evidence from an operations research.

BACKGROUND: In almost every major urban city, thousands of people live in overcrowded slums, streets, or other public places without any health services. Bangladesh has experienced one of the highest rates of urban population growth in the last three decades compared to the national population growth rate. The numbers of the urban poor and street-dwellers are likely to increase at least in proportion to the overall population growth of the country. The street-dwellers in Bangladesh are extremely vulnerable in terms of their health needs and healthcare-seeking behaviours. In Bangladesh, there is no health service-delivery mechanism targeting this marginalized group of people. This study, therefore, assessed the effectiveness of two models to provide primary healthcare (PHC) services to street-dwellers. METHODS: This study of experimental pre-post design tested two models, such as static clinic and satellite clinics, for providing PHC services to street-dwellers in the evening through paramedics in Dhaka city during May 2009-April 2010. Both quantitative and qualitative techniques were used for collecting data. Data were analyzed comparing before and after the implementation of the clinics for the assessment of selected health and family-planning indicators using the statistical t-test. Services received from the model l and model 2 clinics were also compared by calculating the absolute difference to determine the relative effectiveness of one model over another. RESULTS: The use of healthcare services by the street-dwellers increased at endline compared to baseline in both the model clinic areas, and the difference was highly significant (p < 0.001). Institutional delivery among the female street-dwellers increased at endline compared to baseline in both the clinic areas. The use of family-planning methods among females also significantly (p < 0.001) increased at endline compared to baseline in both the areas. CONCLUSIONS: As the findings of the study showed the promise of this approach, the strategies could be implemented in all other cities of Bangladesh and in other countries which encounter similar problems.

Effects of vibration, feed force and exposure duration on operators performing drilling task.

It has been shown that vibration level, feed force, and exposure duration cause unfavourable effects on the work performance when hand-held vibrating tools are used by operators. Present study analyzed the effects of these variables on the heart rate and blood pressure of the operators carrying out the drilling task. Under three different levels of vibration (0.3, 0.5, and 1 m/s2), the operators performed the drilling for 3 minutes with three different levels of feed force (100, 200, and 300 N) in study 1, and for three different durations (10, 15, and 20 min) with a feed force of 200 N in study 2. Thirty male subjects participated in the two studies and data were analyzed on the basis of two factor repeated measure kind of experimental design. Results showed that in the kind of drilling task undertaken the level of vibration was statistically significant. However, the main effects of feed force and vibration exposure duration were statistically insignificant. These findings are discussed in the light of previous researches conducted on the subject.