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Design, synthesis, and biological evaluation of a novel class of fluorescein-based N-glycosylamines.
Carbohydr Res
; 346(13): 1776-85, 2011 Sep 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21714960
RESUMO
A series of fluorescein-based N-glycosylamines was synthesized from the corresponding fluorescein amine and a partially protected d-glucose. The physiochemical investigation of these compounds by spectral and morphological studies reveals their gelation potential. The exclusive localization of fluorescence in the cytoplasm through cell imaging studies reveals the anti-cancer potentials of N-glycosylamines.