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2.
Artigo em Russo | MEDLINE | ID: mdl-7771152

RESUMO

A high degree of resistance to cholera diagnostic phages and carriership of prophages characteristic of V. cholerae eltor strains vct+ were shown to be the specific features V. cholerae isolated in Daghestan during the period of June-October 1994. Among the strains under study, isolated respectively in 12 and 18 out of 19 regions of Daghestan, a high proportion was found to have resistance to tetracycline (65%) and chloramphenicol (28.6%). Moreover, some strains were found to be resistant to furagin and erythromycin. Out of 242 strains resistant to antibacterial preparations, 163 strains were found to have multiple resistance. Gentamicin, cipropfloxacin and doxicycline were shown to have high in vitro activity with respect to the strains under study.


Assuntos
Vibrio cholerae/isolamento & purificação , Antibacterianos/farmacologia , Tipagem de Bacteriófagos , Portador Sadio/microbiologia , Cólera/microbiologia , Daguestão , Resistência Microbiana a Medicamentos , Microbiologia Ambiental , Humanos , Testes de Sensibilidade Microbiana , Vibrio cholerae/classificação , Vibrio cholerae/efeitos dos fármacos
3.
Artigo em Russo | MEDLINE | ID: mdl-6342310

RESUMO

V. eltor strain 1310, serotype Ogawa, an original strain capable of producing cholera enterotoxin (exotoxin) in synthetic culture media, has been obtained. The exotoxin produced by this strain can be obtained in large amounts and used as cholerigenic toxoid for immunization against cholera.


Assuntos
Toxina da Cólera/isolamento & purificação , Enterotoxinas/isolamento & purificação , Vibrio cholerae/metabolismo , Animais , Técnicas Bacteriológicas , Cólera/microbiologia , Toxina da Cólera/biossíntese , Toxina da Cólera/farmacologia , Meios de Cultura/metabolismo , Cobaias , Humanos , Masculino , Coelhos , Sorotipagem , Absorção Cutânea/efeitos dos fármacos , Vibrio cholerae/classificação , Vibrio cholerae/isolamento & purificação
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