Lidocaine Induced Laryngeal Angioedema in Sweet Syndrome: Is it incidental or anticipated?

Sweet's Syndrome is a rare inflammatory disease in which there is neutrophilic infiltration of the cutaneous tissue with or without vasculitis. Rarely, the extra-cutaneous tissue is affected. In the ENT Clinic, Sweet Syndrome can have variable manifestations due to the possible co-existing vasculitis and autoimmune diseases. We hereby report a middle-aged male patient with active Sweet's Syndrome and developed laryngeal angioedema after receiving laryngeal wash with lidocaine for a routine video laryngoscopy. Supplementary Information: The online version contains supplementary material available at 10.1007/s12070-022-03396-4.