RESUMO
Platelets-endothelial cells interaction appears to cause vascular damage in diabetes. Platelet aggregation was studied in 24 diabetic children and adolescents (mean age: 12.2 years, mean duration of diabetes: 3.3 years), with only one presenting microangiopathy complications (retinopathy). Platelet aggregation was found to be normal, suggesting that there is usually no platelet hyperactivity in diabetic children.
Assuntos
Diabetes Mellitus Tipo 1/sangue , Agregação Plaquetária , Difosfato de Adenosina , Adolescente , Adulto , Criança , Pré-Escolar , Diabetes Mellitus Tipo 1/fisiopatologia , Feminino , Humanos , Masculino , RistocetinaRESUMO
The authors studied the specificity and the sensitivity of serum anti-reticulin IgA type antibody determination for the diagnosis of coeliac disease in diabetic patients. They observed a frequency of 11.1% coeliac disease among a group of 54 type I juvenile diabetic patients. The search for serum antireticulin IgA type antibodies appears to be an efficient method for identifying patients with coeliac disease; it has a specificity of 98% and a sensitivity of 95%. This marker appears to be particularly well suited for the identification of asymptomatic forms, and also for surveillance of diet during the course of coeliac disease.
Assuntos
Anticorpos/análise , Doença Celíaca/etiologia , Diabetes Mellitus Tipo 1/complicações , Reticulina/imunologia , Adolescente , Adulto , Doença Celíaca/imunologia , Criança , Pré-Escolar , Diabetes Mellitus Tipo 1/imunologia , Imunofluorescência , Humanos , Imunoglobulina A/análise , Imunoglobulina G/análiseRESUMO
The authors report a case of calcifications of an intervertebral cervical disk in a 12-year-old boy. A torticollis was the clinically revealing event. As in the majority of the published cases, the etiology remained unknown and the evolution was simple with complete regression of the calcifications.