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J Public Health (Oxf) ; 43(1): 3-8, 2021 04 12.
Artigo em Inglês | MEDLINE | ID: mdl-32940328

RESUMO

BACKGROUND: The recent pandemic by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global emergency. There is large number of asymptomatic cases of SARS-CoV-2 that are not reported. Hence, serological evidence of SARS-CoV2 antibodies is warranted for a better estimation of the actual number of infected patients to limit the disease spread and to get an idea of herd immunity. METHODS: This is a cross-sectional study conducted from May 2020 to July 2020 at National Institute of Blood Diseases at Pakistan. The study includes healthcare workers (HCWs), community and industrial workers. The anti-SARS-CoV-2 test was performed by electrochemiluminescence immunoassay analyzer. RESULTS: A total of 1675 samples have been received from three groups of population. The percentage positivity for industrial employees is high (50.3%) for HCW (13.2%) and community population (34%).Total percentage for positive antibodies result is ~36%. CONCLUSION: Our seroprevalence is 36%, which still far from herd immunity that needs to be at least 60-70% in population. If we consider acquiring 60% seroprevalence in next few months, then herd immunity is not far from reality, provided the antibodies did not decline with time. Although the current study is based on a small sample of participants, the findings suggest a study with larger population to implement stronger and targeted interventions.


Assuntos
COVID-19/epidemiologia , Imunidade Coletiva , Adolescente , Adulto , Anticorpos Antivirais/sangue , COVID-19/imunologia , Estudos Transversais , Feminino , Pessoal de Saúde , Humanos , Indústrias , Masculino , Pessoa de Meia-Idade , Paquistão/epidemiologia , SARS-CoV-2 , Estudos Soroepidemiológicos , Adulto Jovem
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