[Distant radiotherapy in rheumatoid arthritis]. / Distantsionnaia luchevaia terapiia pri revmatoidnom artrite.

During an open controlled study of 20 patients with rheumatoid arthritis (resistant forms) their lymph nodes were irradiated at a dose of 7.5 Gy. Clinical improvement, including reduced morning rigidity, the number of inflamed joints, and Riccis index, was noted shortly after therapy and 6 mos. after irradiation in 50% of the patients. Immunosuppression and moderate lymphopenia were noted in all of them. Of the side-effects there was nausea that disappeared without additional treatment. A conclusion has been made that irradiation of the lymph nodes at a total dose of 7.5 Gy is equally effective but less toxic than irradiation of 20 Gy.

[Combined treatment of patients with osteogenic sarcoma using local UHF-hyperthermia]. / Kombinirovannoe lechenie bo'lnykh s osteogennoi sarkomoi s primeneniem loka'lnoi UVCh-gipertermii.

The authors present their results of combined treatment of 85 patients with osteogenic sarcoma. The results are analysed according to the method of treatment in 3 groups of the patients who had been administered different total focus doses acting on the tumour. Besides chemical and radial therapy and surgical treatment local UHF-hyperthermia was used as a modifier in the complex of therapeutic measures. It has been demonstrated that the use of local UHF-hyperthermia does not increase the risk of metastatic spreading, allows to reduce the radiation dose and by influencing the primary tumour contributes to better treatment results.

[Tele-gamma irradiation of subdiaphragmatic lymph nodes in rheumatoid arthritis]. / Distantsionnoe gamma-obluchenie poddiafragmal'nykh limfaticheskikh uzlov pri revmatoidnom artrite.

The authors described methods of gamma-beam therapy of the retroperitoneal lymph nodes in patients with rheumatoid arthritis and therapeutic results. The para-aortal and ilioinguinal lymph nodes were irradiated in 20 patients at a dose of 20 Gy during 2 weeks. Half of the patients demonstrated improved general status with a decrease of disease activity and normalization of the articular syndrome.

[Changes in the lungs in patients with lymphogranulomatosis, Stages I-II, following combination therapy]. / Izmeneniia v legkikh u bol'nykh limfogranulematozom I-II stadii posle kombinirovannogo lecheniia.

Early and late pulmonary changes in 140 patients with Hodgkin's disease, Stages I-II, following combined treatment (polychemo- and radiotherapy) are analysed. Radiation pulmonitis and local paramediastinal fibrosis occur less frequently and they are less noticeable in combined therapy as compared to similar changes developing after radiation therapy only. It can be due to the fact that a course of polychemotherapy at its first stage results in a considerable decrease of the mediastinal lymph nodes (up to their complete regression) thus making it possible to shape irradiation fields of smaller sizes and to decrease the volume of pulmonary tissue to be irradiated.

[Early and late changes in the lungs following irradiation of the mediastinum (based on studies of patients with lymphogranulomatosis)]. / Rannie i pozdnie izmeneniia legkikh posle oblucheniia sredosteniia (po materialam issledovaniia bol'nykh limfogranulematozom).

In a group of 180 patients with Hodgkin's disease who received irradiation of the mediastinum, 23 (12.7%) developed shortly after that (up to 6 mos.) the signs of radiation pulmonitis, later on 171 (95%) local paramediastinal fibrosis. Radiation changes revealed were either subclinical or asymptomatic. The frequency of early radiation changes and the extent of local fibrosis depend on the volume of irradiated pulmonary tissue. The summary focal doses within the range of 31-45Gy are less important.

[Diagnostic laparotomy in patients with lymphogranulomatosis]. / Diagnosticheskaia laparotomiia u bol'nykh limfogranulematozom

The authors' experience with 80 diagnostic laparotomies with the removal of the spleen, performed in patients showing lymphogranulomatosis, is summarized. As a result of surgery in 40 patients the stage of the diseases was revised and therapeutic policy was altered, that is felt to warrant the risk of surgical intervention.