[Comparative analysis of metabolites of Candida albicans and other clinically important fungi using gas chromatography]. / Sravnitel'nyi analiz produktov metabolizma Candida albicans i drugikh klinicheski znachimykh gribov metodom gazovoi khromatografii.

Qualitative and quantitative compositions of metabolites of the fungi belonging to the genera Candida, Cryptococcus, Geotrichum, Aspergillus, Penicillium, Fusarlum, Actinomyces, Sporotrichum and Alternaria were studied. It was shown that the composition of carbohydrates, alcohols, volatile and nonvolatile fatty acids and amines after the fungi cultivation was specific of every genus. The in vitro investigation of the entire spectra of the metabolites such as monosugars, alcohols, volatile and nonvolatile acids and amines for the determination of the markers specific of the genus Candida demonstrated that for the indication of C. albicans the informative components were arabinitole (sugar alcohol), ethyl and isoamyl alcohols and nonvolatile fatty acids (fumaric, amber, oxalacetic and pyruvic). For the diagnosis of candidiasis it is advisable to determine D-arabinitole in biological fluids as a marker of Candida infection.

[Identification of Mycobacterium tuberculosis by the method of gas-liquid chromatography]. / Identifikatsiia mikobakterii metodom gazozhidkostnoi khromatografii.

Gas-liquid chromatography was used to study the composition of fatty acids and hydrocarbons of different types of Mycobacteria, including M. tuberculosis, opportunistic Mycobacteria and acid-fast saprophytes. In terms of composition of fatty acids and hydrocarbons, clinical and laboratory strains of M. tuberculosis are very similar. The cellular higher fatty acids of M. tuberculosis differ much from those of opportunistic Mycobacteria and acid-fast saprophytes. The findings can be used for the identification and differentiation of different types of Mycobacteria.