RESUMO
Parameters of chemiluminescence of lipid peroxidation (LP), induced by hydrogen peroxide in the blood serum of oncology patients (n = 60), were examined in the process of their combined therapy. During the dynamic observations, complete correlations were found between the peculiarities of manifestations and of the clinical course of the tumor process, the level of free-radical LP and the antioxidants of blood serum. A comprehensive assessment of all mentioned indices can be used to monitor the efficiency of a conducted therapy.
Assuntos
Neoplasias da Mama/sangue , Peroxidação de Lipídeos , Lipídeos/sangue , Antioxidantes/metabolismo , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/terapia , Terapia Combinada , Feminino , Humanos , Medições LuminescentesRESUMO
Immediate results of complex treatment were studied in 185 patients with stage IIIa, b (T1-2N2M0 and T3N0-2M0) nodular breast cancer. Preoperative chemoradiation treatment incorporated microwave procedure. All patients had been radically mastectomized after Patey. The analysis included assessment of response and degree of treatment-induced pathomorphosis, versus age, menstrual function, site and histologic structure of tumor. Microwave procedure proved an effective component of complex treatment of stage IIIa, b breast cancer. Good results were obtained in patients aged 51-60 suffering adenocarcinoma.