[Proliferativeactivity biorhythms of museum and hospital strains of microorganisms].

In series of experiments intraday dynamics of proliferative activity of museum and hospital strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa was revealed. Statistically significant circadian and ultradian biorhythms in these strains were detected. Chronoinfrastructure of hospital strains differed from museum ones. This finding allows to detect hospital strains of these bacteria.

[Etiology of purulent infections in the Tiumen' region based on hospital data]. / Etiologiia gnoinykh infektsii v Tiumenskoi oblasti po dannym bol'nichnogo statsionara.

A study of laboratory findings for 474 examined patients, who were discharged from the Surgical Department of the Tyumen Regional Clinical Hospital, showed that S. aureus caused the infectious processes in 31.7% of the examinees. Oxacyllinresistant strain S aureus made up 9.7%.e examinees, and 22.6% of pathologies were caused in them by E. coli. E. coli was frequently found to be combined with polyresistant strains E. faecalis, E. faecium, K. pneumoniae and P. aeruginosa, which could be explained by the circulation of hospital strains within a hospital and by the selection of microorganisms with a high resistance level to antibacterial drugs.

[Etiology of purulent septic diseases and the antibiotic resistance of the isolated causative agents]. / Etiologiia gnoino-septicheskykh zabolevanii i antibiotikorezistentnost' vydeliaemykh vozbuditelei.

Among the causative agents of purulent septic diseases in the surgical hospital, 25 microbial species were isolated; of these, the prevailing species were Staphylococcus aureus (19.86 +/- 1.07%), Escherichia coli (16.5 +/- 0.99%) and Pseudomonas aeruginosa (10.06 +/- 0.8%). From environmental objects in the hospital 14 microbial species were isolated, among them bacteria of the genus Enterobacter (27 +/- 1.7%), E. coli (19.07 +/- 1.48%), S. aureus (14.7 +/- 1.31%), Klebsiella pneumoniae (13.73 +/- 1.31%), P. aeruginosa (7.33 +/- 0.98%). During 3 years of observation the isolation rate of K. pneumoniae from different environmental objects was found to increase threefold to 24.7 +/- 2.7%. The results of the study of the microbial picture in surgical hospitals, as well as the antibiotic resistance of circulating causative agents, should be borne in mind while taking epidemic control measures.