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In this research, a systematic, integrated framework was developed to evaluate the biophysical state and vulnerability intensity of groundwater supply ecosystem service (GSES) regarding excessive groundwater withdrawal in the Mashhad plain located in the northeastern of Khorasan Razavi province in Iran. At first, following an indexing approach, the biophysical aspects of the ecosystem, including capacity, flow, and the benefits of GSES, were analyzed. Afterward, the relationship between the capacity and flow ecosystem service (ES) was assessed to identify ecosystem's sustainability status. Furthermore, GSES stability was spatially shown. Finally, GSES vulnerability and its associated ESs was assessed based on 3D model of vulnerability via indexing three components of exposure, sensitivity, and adaptive capacity. The final map spatially indicated the zoning of groundwater ecosystem services' vulnerability intensity in Mashhad Plain. The outcomes indicate a high and very high vulnerability in more than 35% of studying area. The results indicate that about 18%, 30%, and 15% of studying land show moderate, low, and no vulnerability, respectively. Finally, it was observed that due to groundwater's over-extraction, supplying the aquifer ecosystem services was disrupted. This method can be used as a solution for the sustainable management of groundwater resources, especially in the arid and semi-arid countries facing the depletion of water resources.
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Ecossistema , Água Subterrânea , Monitoramento Ambiental , Água , Recursos Hídricos , Abastecimento de ÁguaRESUMO
BACKGROUND: Cardiovascular disease (CVD) is the principal cause of mortality and disability in Iranian adults. We aimed to evaluate the relationship between dietary patterns and CVD incidence in a large sample of adults in northeastern Iran. METHODS: The present study comprised a prospective study of 5706 CVD-free men and women aged 35-65 years who participated in a cohort study. All of the participants were followed up for a 6-year period. Dietary patterns were derived from a 65-item validated food frequency questionnaire and the factor analysis method was used to determine dietary patterns. RESULTS: We identified two major dietary patterns: (i) a Balanced dietary pattern (a high intake of green leafy vegetables, other vegetables, fruits, dairy products, red meats, poultry, seafoods, legumes and nuts, as well as a low intake of sugar) and (ii) a Western dietary pattern (a high intake of sugar, tea, egg, snacks, fast foods, potato, carbonated beverages, pickled foods, organs meat and butter) by factor analysis. The hazard ratio (HR) and 95% confidence intervals (CIs) of total CVD in the highest versus lowest tertiles of the Balanced pattern were 1.29 (95% CI = 0.67-2.47; P = 0.44). The HR and 95% CIs of CVD in the highest versus lowest tertiles of Western pattern were 2.21 (95% CI = 1.08-4.45; P = 0.03). CONCLUSIONS: During the 6-year follow-up, we found that adherence to a Balanced dietary pattern was not significantly associated with CVD events. However, adherence to a Western dietary pattern was associated with a significantly increased risk of CVD events and its associated risk.
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Doenças Cardiovasculares/epidemiologia , Comportamento Alimentar/fisiologia , Adulto , Idoso , Doenças Cardiovasculares/diagnóstico , Estudos de Coortes , Registros de Dieta , Dieta Saudável , Dieta Ocidental/efeitos adversos , Exercício Físico , Feminino , Humanos , Irã (Geográfico)/epidemiologia , Masculino , Pessoa de Meia-Idade , Modelos de Riscos Proporcionais , Estudos Prospectivos , Fatores de Risco , Inquéritos e QuestionáriosRESUMO
BACKGROUND: Considering the limited available resources, high cost of the helicopter emergency medical service (HEMS), and high load of trauma patients especially in our centers, a careful assessment of HEMS in our center seemed to be necessary for trauma patients. METHODS: From April 2001 to September 2007, the data of all patients transferred by HEMS were extracted including: Annual number of services, clinical category, number of proper or improper services, and rescue time for HEMS and ground ambulance. The criteria for the properly transferred group included: Death or being operated in the first 24 hours of admission, admission in ICU care units, and transfer of more than three patients in one mission. Others were considered as improper group. RESULTS: In this period through 185 flights, 225 victims were transferred. The most common reason of HEMS dispatching was trauma. The most difference of rescue time between ground ambulance and HEMS was recorded in Lamerd that was transferring patients with HEMS needed 3 hours less than ground ambulance. However, in Sarvestan, Dashte-Arjan, and Marvdasht, transferred patients with ground ambulance needed less time than air transfer. Most of transferred patients were from Kazeroon, Nourabad and Lamerd respectively while 46.3% of patients were in the proper group, and the rest were considered as improper group. CONCLUSION: Our study revealed that helicopter dispatch to the cities like Lamerd, Lar, Khonj, Abadeh can be more effective, whereas, for the towns like Marvdasht, Dashte-Arjan, Sarvestan, Sepidan, Saadatshar, Tang Abolhayat use of HEMS should be limited to specific conditions. Our study showed inclusion of physicians in the decision making team increased the number of transferred cases.
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OBJECTIVE: To validate the Knee injury and Osteoarthritis Outcome Score (KOOS) for the assessment of competitive athletes with higher level sports activities after anterior cruciate ligament (ACL) reconstruction. METHODS AND MEASURES: Fifty-seven athletes (39 males and 18 females; age, 25.6 ± 3.4 years; height, 179.6 ± 7.4 cm; weight, 77.6 ± 9.8 kg) after ACL reconstruction were asked to complete the Persian KOOS and Short Form-36 (SF-36) questionnaires in the test session. To evaluate test-retest reliability, all participants filled out the KOOS and SF-36, 6-8 days after the first visit. The properties of the KOOS in terms of reliability [Intraclass Correlation Coefficient (ICC)], internal consistency (Cronbach's alpha), dimensionality (item-scale correlation) and construct validity (Spearman's rank correlation) were evaluated. RESULTS: No floor or ceiling effect was observed. The ICCs (S.E.M.s) of the KOOS subscales were: Pain 0.93 (2.2), Symptoms 0.85 (3.1), Activities of Daily Living 0.91 (2.9), Function in Sport and Recreation 0.75 (2.1) and Knee-related Quality of Life 0.89 (2.6). The Cronbach's alphas of the KOOS subscales were: Pain 0.91, Symptoms 0.75, Activities of Daily Living 0.96, Function in Sport and Recreation 0.86 and Knee-related Quality of Life 0.74. Spearman's rank correlations between the subscales of the KOOS and representative subscales of the SF-36 ranged from 0.40 to 0.79. CONCLUSION: This study illustrates the validity and reliability of the KOOS in measuring the functional status and quality of life of athletes after ACL reconstruction. This study further validates the use of the KOOS in highly competitive athletes in research on knee injuries.
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Ligamento Cruzado Anterior/cirurgia , Avaliação da Deficiência , Traumatismos do Joelho/fisiopatologia , Osteoartrite do Joelho/fisiopatologia , Adulto , Lesões do Ligamento Cruzado Anterior , Atletas , Feminino , Humanos , Traumatismos do Joelho/diagnóstico , Traumatismos do Joelho/cirurgia , Masculino , Osteoartrite do Joelho/diagnóstico , Osteoartrite do Joelho/cirurgia , Avaliação de Resultados em Cuidados de Saúde , Recuperação de Função Fisiológica/fisiologia , Reprodutibilidade dos Testes , Adulto JovemRESUMO
To evaluate the efficacy of sildenafil in the treatment of neurogenic erectile dysfunction (ED) secondary to upper motor neuron (UMN) and lower motor neuron (LMN) spinal cord injury (SCI). After taking consents 105 patients suffering from ED were enrolled in this prospective study. Seventy-two patients had signs and symptoms of UMN and 33 patients had signs and symptoms of LMN or mixed (UMN and LMN) spinal cord injuries. The patients took 50-100 mg sildenafil or placebo tablet at least 45 min before sexual intercourse. Based on a IIEF questionnaire, success in achieving erection adequate for sexual intercourse was compared between sildenafil and placebo groups in UMN and non-UMN spinal cord injuries. In patients with UMN disease, sildenafil was effective in 82% of patients and its efficacy was statistically higher than placebo (82 vs. 25%, p < 0.05). Twenty-eight per cent of patients with non-UMN disease had a favourable response to sildenafil that was not statistically different from placebo. Sildenafil seems more effective in the treatment of neurogenic ED secondary to UMN spinal cord injury compared with that secondary to LMN injury. Actually, its efficacy on LMN injuries does not seem different from placebo and administration of this treatment may not be effective in spinal cord injury which has caused LMN symptoms.
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Disfunção Erétil/tratamento farmacológico , Paraplegia/complicações , Inibidores de Fosfodiesterase/uso terapêutico , Piperazinas/uso terapêutico , Traumatismos da Medula Espinal/complicações , Sulfonas/uso terapêutico , Adulto , Disfunção Erétil/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Purinas/uso terapêutico , Citrato de SildenafilaRESUMO
A voting model (or a generalization of the Glauber model at zero temperature) on a multidimensional lattice is defined as a system composed of a lattice, each site of which is either empty or occupied by a single particle. The reactions of the system are such that two adjacent sites, one empty, the other occupied, may evolve to a state where both of these sites are either empty or occupied. The continuum version of this model in a D-dimensional region with a boundary is studied, and two general behaviors of such systems are investigated, the stationary behavior of the system, and the dominant way of relaxation of the system toward its stationary state. Based on the first behavior, a static phase transition (discontinuous changes in the stationary profiles of the system) is studied. Based on the second behavior, a dynamical phase transition (discontinuous changes in the relaxation times of the system) is studied. It is shown that the static phase transition is induced by the bulk reactions only, while the dynamical phase transition is a result of both bulk reactions and boundary conditions.
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The most general one dimensional reaction-diffusion model with nearest-neighbor interactions that can be solved exactly through empty-interval method has been introduced. Assuming translationally invariant initial conditions, the probability that n consecutive sites are empty, E(n), has been exactly obtained. Here, however, we do not consider reactions changing two empty neighboring sites. In the thermodynamic limit, the large-time behavior of the system has also been investigated. Releasing translationally invariance, the evolution equation for the probability that n consecutive sites, starting from the site k, are empty, E(k,n), is obtained. In the thermodynamic limit, the large time behavior of the system is also considered. Finally, the continuum limit of the model is considered and the empty-interval probability function is obtained.
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Autonomous multispecies systems with more-than-two-neighbor interactions are studied. Conditions necessary and sufficient for the closedness of the evolution equations of the n-point functions are obtained. The average numbers of the particles at each site for one species and three-site interactions, and its generalization to the more-than-three-site interactions, are explicitly obtained. Generalizations of the Glauber model in different directions, using generalized rates, generalized numbers of states at each site, and generalized numbers of interacting sites, are also investigated.
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An asymmetric generalization of the zero-temperature q-state Potts model on a one-dimensional lattice, with and without boundaries, has been studied. The dynamics of the particle number, and especially the large time behavior of the system, has been analyzed. In the thermodynamic limit, the system exhibits two kinds of phase transitions, a static and a dynamic phase transition.
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A family of one-dimensional multispecies reaction-diffusion processes on a lattice is introduced. It is shown that these processes are exactly solvable, provided a nonspectral matrix equation is satisfied. Some general remarks on the solutions to this equation, and some special solutions are given. The large-time behavior of the conditional probabilities of such systems is also investigated.
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Biofísica/métodos , Algoritmos , Difusão , Matemática , Modelos TeóricosRESUMO
An asymmetric generalization of the zero-temperature Glauber model on a lattice is introduced. The dynamics of the particle-density and especially the large-time behavior of the system is studied. It is shown that the system exhibits two kinds of phase transitions, a static one and a dynamic one.
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Multispecies reaction-diffusion systems, for which the time evolution equations of correlation functions become a closed set, are considered. A formal solution for the average densities is found. Some special interactions and the exact time dependence of the average densities in these cases are also studied. For the general case, the large-time behavior of the average densities has also been obtained.
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We consider a two-parameter family of asymmetric exclusion processes for particles living on a continuous one-dimensional space. Using the Bethe ansatz, the exact solution to the master equation, and from that the drift and the diffusion rate in the two particle sector, are obtained.