[Cholinesterase activity as a prognostic test in phalloidine mushroom poisoning]. / Kholinesteraznata aktivnost kato prognostichen test pri faloidna gubna intoksikatsiia.

The phalloidine mushroom poisoning is an exogenic intoxication with specific action of the mushroom toxins on the liver and its functions. The dynamic follow up of serum cholinesterase activity in patients with phalloidine intoxication revealed that it was significantly decreased in the patients who died in comparison to those who survived. In the patients who survived and recovered the serum cholinesterase was moderately decreased and later increased. As a protein product synthesized in the liver the serum cholinesterase is a good marker of the protein-synthesizing function of the liver in patients with phalloidine intoxication and may be used as a prognostic test for its outcome.

[Functional disorders and structural changes in the liver in Amanita phalloides poisoning]. / Funktsionalni smushteniia i strukturni izmeneniia v cherniia drob pri faloidna gubna intoksikatsiia.

The liver functional disorders and structural changes were studied in 17 patients (children 6, adults 11, 4 to 70 years of age) with phalloidine intoxication. The clinical course of this severe and lethal exogenic intoxication, its characteristic clinical and laboratory features are discussed in relation to the morphological changes of the liver. The structural changes are similar in all patients independently of their age and the time of death. They are presented by fatty degeneration, acute toxic liver dystrophy and centrilobular necroses. These changes are produced by the specific action of the phalloidine toxins on the liver.

[Acute poisoning by tricyclic antidepressants in childhood]. / Ostri otravianiia s niakoi tritsiklichni antidepresanti v detskata vuzrast.

The authors share their experience in the clinical observation and treatment of 72 children with acute intoxications by tricyclic antidepressants. The syndromes, forming the clinical picture of the acute intoxication at that age were the cerebrotoxic, cholinolytic and cardiotoxic ones. According to their content, the intoxication advanced in three forms: light, moderately severe and severe. The complex application of the therapeutic methods from the unified therapeutic system for the treatment of acute intoxications gave lethality of 5.5%, determined, primarily, by the late admittance of the children for hospital treatment in a state of decompensated phase of exotoxic shock. The anamnestic data for administration of tricyclic preparation in toxic and lethal doses is a signal for hospitalization of the chill with the inclusion of all necessary procedures with a dynamic follow up of its state.

[Our experience with the dialysis treatment of phalloides fungal poisoning]. / Nashiiat opit a dializno lechenie na faloidnata gubna intoksikatsiia.

The authors present their practical experience in the treatment of phalloid fungal intoxication via dialysis methods of treatment, included within the complete therapeutic system of that kind exogenous intoxication. The peritoneal dialysis and hemodialysis, with consideration given to the patient's state, enables the reduction of the extremely high lethality. Their early application guarantees higher effectiveness of the dialysis methods of treatment.