Assuntos
Hiperpigmentação/patologia , Terminologia como Assunto , Adolescente , Humanos , Masculino , TóraxRESUMO
Benign endometroid cystadenofibroma of the ovary is a rare tumour with few reported cases. The association of endometroid cystadenofibroma with endometrial cystic glandular hyperplasia has not been previously reported to authors' knowledge. We are reporting a 75-year-old postmenopausal woman who presented with a large abdominopelvic mass corresponding to 30 weeks size gravid uterus and postmenopausal bleeding. She has a well-oestrogenised vagina. Ultrasound pelvis revealed a large cystic mass extending from pelvis to epigastrium with no solid component and few incomplete septations and no internal echoes. MRI findings showed mainly cystic component with few moderately enhancing, fine, incomplete septa. Endometrial aspiration reported histopathology of cystic glandular hyperplasia without atypia. Serum oestrogen level reported to be high (210 pg/mL). Hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathology of the specimen revealed benign endometroid cystadenofibroma. She remained asymptomatic and disease free during her 6-month follow-up.
Assuntos
Cistoadenofibroma/diagnóstico , Hiperplasia Endometrial/etiologia , Neoplasias do Endométrio/diagnóstico , Neoplasias Ovarianas/diagnóstico , Pós-Menopausa , Hemorragia Uterina/etiologia , Idoso , Cistoadenofibroma/complicações , Cistoadenofibroma/cirurgia , Diagnóstico Diferencial , Neoplasias do Endométrio/complicações , Neoplasias do Endométrio/cirurgia , Feminino , Humanos , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/cirurgia , Resultado do TratamentoRESUMO
We report a 4-year-old boy presenting with a tense massive ascites and large hydrocele. History and physical examination were unremarkable. Routine laboratory studies were normal. Abdominal ultrasonography revealed massive ascites. Contrast CT was suggestive of a large cyst covering the entire peritoneal cavity. At laparotomy, a large cystic tumor was found extending into the scrotum through the left inguinal ring. Histopathologic examination diagnosed the tumor as a cystic lymphangiomatous hemartoma. Although abdominal lymphangiomas are seen in children, but presenting as massive ascites with hydrocele is very rare.
Assuntos
Ascite/diagnóstico , Hamartoma/patologia , Linfangioma/patologia , Neoplasias Peritoneais/patologia , Hidrocele Testicular/diagnóstico , Ascite/cirurgia , Pré-Escolar , Diagnóstico Diferencial , Seguimentos , Hamartoma/diagnóstico , Hamartoma/cirurgia , Humanos , Laparotomia , Linfangioma/diagnóstico , Linfangioma/cirurgia , Masculino , Neoplasias Peritoneais/diagnóstico , Neoplasias Peritoneais/cirurgia , Medição de Risco , Índice de Gravidade de Doença , Hidrocele Testicular/cirurgia , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Ultrassonografia DopplerRESUMO
Donovanosis is endemic in various parts of the world. Although donovanosis has been reported to co-exist with the human immunodeficiency virus (HIV) infection, to our knowledge there have been no reports of co-existent squamous cell carcinoma (SCC) in an HIV positive patient. In our case the patient did not respond to treatment for donovanosis and on biopsy we realized that the patient had coexistent SCC, which is hitherto unreported with granuloma inguinale.
Assuntos
Carcinoma de Células Escamosas/complicações , Granuloma Inguinal/complicações , Infecções por HIV/complicações , Neoplasias Penianas/complicações , Neoplasias Cutâneas/complicações , Amputação Cirúrgica , Antibacterianos/uso terapêutico , Fármacos Anti-HIV/uso terapêutico , Terapia Antirretroviral de Alta Atividade , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/terapia , Transformação Celular Neoplásica , Quimioterapia Adjuvante , Terapia Combinada , Progressão da Doença , Doxiciclina/uso terapêutico , Granuloma Inguinal/tratamento farmacológico , Granuloma Inguinal/patologia , Infecções por HIV/diagnóstico , Infecções por HIV/tratamento farmacológico , Humanos , Masculino , Neoplasias Penianas/patologia , Neoplasias Penianas/terapia , Radioterapia Adjuvante , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/terapia , Úlcera Cutânea/etiologia , Adulto JovemRESUMO
Granulocytic sarcoma of the female genital tract is a rare occurrence. A case of a perimenopausal female is presented who reported with a history of menorrhagia with a lump in the abdomen. A diagnosis of fibroid uterus was made but laparotomy findings were suggestive of inoperable ovarian malignancy with metastases. Postoperatively the patient suddenly became very anemic. Hematological investigations and histopathological reports from ovaries, myometrium, endometrium and intraperitoneal deposits all revealed acute myeloid leukemia. The patient received two cycles of chemotherapy but later succumbed to her disease. Extrauterine causes of menorrhagia should be considered before instituting definitive treatment. Preoperative induction chemotherapy may be more successful in cases of granulocytic sarcoma who tend to have a poor prognosis.
Assuntos
Neoplasias dos Genitais Femininos/diagnóstico , Neoplasias Peritoneais/secundário , Sarcoma Mieloide/diagnóstico , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Evolução Fatal , Feminino , Neoplasias dos Genitais Femininos/terapia , Procedimentos Cirúrgicos em Ginecologia , Humanos , Neoplasias Peritoneais/terapia , Sarcoma Mieloide/terapiaRESUMO
We report two sisters, ages 12 and 8 years, with the characteristic clinical and biochemical profile of congenital erythropoietic porphyria (CEP). The disease is inherited as an autosomal recessive. The elder sibling had squamous cell carcinoma arising from the stump of the amputated left arm with metastases to lymph nodes, adrenals, and bone. To our knowledge, this feature has not been described in the English language literature, making our patient the first documented report of CEP with squamous cell carcinoma.