[Increase in DNAase activity in rat urine after intraperitoneal administration of DNAases]. / Povyshenie DNK-aznoi aktivnosti mochi krys posle vnutribriushinnogo vvedeniia DNK-az.

After intraperitoneal administration of DNAase into rats maximal increase in the enzymatic activity was observed in urine within 3-4 hrs. This suggests the ability of DNAase to penetrate through cell barriers without a loss of its biological activity. The importance of the phenomenon is discussed considering possible use of DNAases as protector of the body against heterologous nucleic acids.