1.
Org Lett
; 21(14): 5443-5446, 2019 Jul 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31247758
RESUMO
Nitroaromatics substituted with electron-acceptor or electron-donor groups undergo vicarious nucleophilic substitution with the lithium salt of dichloromethane to provide chloromethyl-substituted nitroaromatics in good to high yields. The methodology represents a new strategy for the synthesis of benzyl chlorides.