[Clinical features of manic-depressive psychosis with organic brain defects]. / Ob osobennostiakh kliniki maniakal'no-depressivnogo psikhoza pri organicheskoi nepolnotsennosti golovnogo mozga.

The authors studied the clinical picture of manic-depressive psychoses in 71 patients who had signs of an organic brain lesion (both anamnestically and clinically), which were confirmed by X-ray and EEG data. It was established that these patients more frequently exhibit atypical forms of affective conditions (anxious--depersonalizational syndromes, angry mania). As a rule, they also have a significant amount of supplementary psychopathological signs in the syndrome structure (dysphorea, obsessions, depersonalization). Such conditions quite often are refractory to therapy and require special therapeutical approaches.

[Use of long-acting lithium carbonate--micalite--in the treatment of affective psychoses]. / Primenenie karbonata litiia prodlennogo deistviia--mikalita--u bol'nykh affektivnymi psikhozami

Micalite (microcapsulated lithium carbonate with a retarded action) was used for the treatment of manic states and the prevention of attacks of manic-depressive psychosis in 40 patients. The preparation was administered once daily. This provided the necessary concentration of lithium in the blood on a stable level. According to its therapeutical effectiveness and the frequency of side-effects micalite does not differ from other lithium preparations with a simgle daily administration of micalite there are much less distubrances in the treament regime.