RESUMO
PURPOSE: This study aimed to investigate the relation between pain and health-related quality of lif e(HRQOL)in cancer patients. METHODS: An internet-based HRQOL survey of 618 patients with different malignancies using the EORTC QLQ-C30 and BPI-SF was performed. Three study groups were formed based on the pain in the previous month: group A comprised patients without pain; group B comprised patients with mild pain; and group C comprised patients with moderate to severe pain. RESULTS: Compared with both groups A and B, group C had significantly low global HRQOL and functioning, which resulted in fatigue, dyspnea, disturbed sleep, and financial difficulties. In addition, the patients in group C were significantly dissatisfied with their cancer medical service compared with the patients in both groups A and B. CONCLUSION: Pain is an important health issue that not only negatively affects the HRQOL but also results in fatigue, dyspnea, disturbed sleep, and financial difficulties in cancer patients. These symptoms may be important key words for HRQOL analysis in clinician-patient interviews.
Assuntos
Neoplasias/complicações , Dor/etiologia , Qualidade de Vida , Adulto , Idoso , Analgésicos Opioides/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias/terapia , Dor/tratamento farmacológico , Inquéritos e Questionários , Adulto JovemRESUMO
The Pictet-Spengler reaction between tryptamine and aldehydes was catalyzed by Dowex 50W-X4 acidic ion-exchange resin. The products were obtained from the resin in high purity by 'catch and release' without the need for separate chromatographic purification.
