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1.
Phys Rev Lett ; 122(12): 128002, 2019 Mar 29.
Artigo em Inglês | MEDLINE | ID: mdl-30978078

RESUMO

Microflows constitute an important instrument to control particle dynamics. A prominent example is the sorting of biological cells, which relies on the ability of deformable cells to move transversely to flow lines. A classic result is that soft microparticles migrate in flows through straight microchannels to an attractor at their center. Here, we show that flows through wavy channels fundamentally change the overall picture. They lead to the emergence of a second, coexisting attractor for soft particles. Its emergence and off-center location depends on the boundary modulation and the particle properties. The related cross-stream migration of soft particles is explained by analytical considerations, Stokesian dynamics simulations in unbounded flows, and Lattice-Boltzmann simulations in bounded flows. The novel off-center attractor can be used, for instance, in diagnostics, for separating cells of different size and elasticity, which is often an indicator of their health status.


Assuntos
Eritrócitos/citologia , Modelos Biológicos , Movimento Celular/fisiologia , Eritrócitos/química , Microfluídica
2.
Phys Rev E Stat Nonlin Soft Matter Phys ; 84(4 Pt 1): 042102, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-22181206

RESUMO

We consider a single Brownian particle confined in a double well potential (DWP) and investigate its response to a linear shear flow by means of the probability density and current determined via numerical solution of the Fokker-Planck equation. Besides a shear-dependent distortion of the probability distribution, we find that the associated current crossing the potential barrier exhibits a convex dependency on the shear rate when the DWP's minima are far apart. With decreasing distance this functional dependency changes from a convex to concave characteristics accompanied with an increase of the probability current crossing the DWP's barrier. Through the difference map of the particle density distribution it is possible to extract the shear-flow-induced contribution to the particle density driving the barrier-crossing current. This may open the possibility to design specific flow profiles to optimize flow-induced activated transport of nanoparticles.

3.
Phys Rev E Stat Nonlin Soft Matter Phys ; 83(6 Pt 1): 062802, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21797426

RESUMO

Using Brownian dynamics simulations, we investigate how hydrodynamic interaction (HI) affects the behavior of tethered polymers in uniform flow. While it is expected that the HI within the polymer will lead to a dependency of the polymer's drag coefficient on the flow velocity, the interchain HI causes additional screening effects. For the case of two polymers in uniform flow with their tether points a finite distance apart, it is shown that the interchain HI not only causes a further reduction of the drag per polymer with decreasing distance between the tether points but simultaneously induces a polymer-polymer attraction as well. This attraction exhibits a characteristic maximum at intermediate flow velocities when the drag forces are of the order of the entropic forces. The effects uniquely attributed to the presence of HI can be verified experimentally.

4.
Phys Rev Lett ; 103(2): 026601, 2009 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-19659227

RESUMO

We present an approach for time-dependent quantum transport based on a self-consistent nonequilibrium Green function formalism. The technique is applied to a ballistic carbon nanotube transistor in the presence of a time-harmonic signal at the gate. In the on state, the dynamic conductance exhibits plasmonic resonant peaks at terahertz frequencies. These vanish in the off state, and the dynamic conductance displays smooth oscillations, a signature of single-particle quantum effects. We show that the nanotube kinetic inductance plays an essential role in the high-frequency behavior.

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