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1.
Intern Med ; 60(23): 3743-3748, 2021 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-34148945

RESUMO

A 57-year-old woman with a sudden-onset seizure was hospitalized. Brain magnetic resonance imaging findings led to a suspicion of leptomeningeal carcinomatosis (LMC) without a brain parenchymal tumor, and abdominal computed tomography showed a tumor in the pancreatic tail. Endoscopic ultrasonography-guided fine needle aspiration of the pancreatic mass revealed adenocarcinoma. Therefore, LMC from pancreatic ductal adenocarcinoma was strongly suspected. She received three courses of nab-paclitaxel plus gemcitabine and whole-brain radiation. Shortly thereafter, she developed a severe consciousness impediment and died. A pathological autopsy showed adenocarcinoma in a wide area of the leptomeninges.


Assuntos
Adenocarcinoma , Carcinomatose Meníngea , Neoplasias Pancreáticas , Adenocarcinoma/tratamento farmacológico , Albuminas/uso terapêutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Autopsia , Desoxicitidina/análogos & derivados , Feminino , Humanos , Carcinomatose Meníngea/tratamento farmacológico , Pessoa de Meia-Idade , Paclitaxel/uso terapêutico , Neoplasias Pancreáticas/tratamento farmacológico , Resultado do Tratamento , Gencitabina
2.
Nihon Shokakibyo Gakkai Zasshi ; 117(11): 1008-1017, 2020.
Artigo em Japonês | MEDLINE | ID: mdl-33177253

RESUMO

Upon abdominal ultrasonography, a woman in her 36 years old was diagnosed with a hypoechoic tumor with a diameter of 60mm surrounding the bile duct in the hepatic portal region. Abdominal computed tomography and magnetic resonance cholangiopancreatography revealed a tumor-like mass in the bile duct. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) confirmed the diagnosis of schwannoma. Considering the lesion location, it appeared to rise from the hepatoduodenal ligament. She was unwilling to undergo tumor resection;however, a year after the diagnosis, no change was observed in the tumor. Here, we report a case of schwannoma in the hepatoduodenal ligament, wherein EUS-FNA was useful for establishing a diagnosis and determining a treatment strategy.


Assuntos
Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico , Neurilemoma , Adulto , Colangiopancreatografia por Ressonância Magnética , Feminino , Humanos , Neurilemoma/diagnóstico por imagem , Neurilemoma/cirurgia , Tomografia Computadorizada por Raios X , Ultrassonografia
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