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1.
Materials (Basel) ; 16(13)2023 Jun 24.
Artigo em Inglês | MEDLINE | ID: mdl-37444874

RESUMO

Carbon aerogel is a promising material in various applications, such as water treatment, insulators, catalysts, and sensors, due to its porosity, low density, conductivity, and good chemical stability. In this study, an inexpensive carbon aerogel was prepared through lyophilization and post-pyrolysis using waste paper. However, carbon aerogel, in the form of short belts, is randomly entangled without a crosslinking agent and has weak mechanical properties, thus limiting its applications, which would otherwise be various. In this paper, a novel strategy is proposed to fabricate a PDMS-coated carbon aerogel (Aerogel@PDMS). Benefiting from microwave heating, precise PDMS coating onto the carbon frame was able to be carried out in a short amount of time. PDMS coating firmly tied the carbon microstructure, maintaining a unique aerogel property without blocking its porous structure. FE-SEM, RAMAN, XPS, and FT-IR were all used to confirm the surface change in PDMS coating. Compressible stability and water contact angle measurement showed that Aerogel@PDMS is a perspective organic solvent absorbent due to its good resilience and its hydrophobicity, and, as a result, its organic solvent absorption capacity and repeated absorption were evaluated, ultimately suggesting a promising material in oil clean-up and pollution remediation in water. Based on our experimental results, we identified elastic carbon aerogels provided by a novel coating technology. In the future, then, the developed carbon/PDMS composite can be examined as a promising option for various applications, such as environmental sensors, virus sensors, and wearable sensors.

2.
Skin Pharmacol Physiol ; 33(3): 82-92, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32535609

RESUMO

BACKGROUND: Essential oil derived from Chamaecyparis obtusa (EOCO) has been used as an alternative treatment for allergy-related diseases due to its immune-modulating characteristics. Clothing has the longest and most intense contact with human skin, and functional fabrics with intrinsic properties have been increasingly implemented in medical applications. Specially designed fabrics may support atopic dermatitis (AD) treatment. In this study, the effects of fabric containing EOCO on AD were investigated using an NC/Nga mouse model. METHODS: The fabric was applied for 6 h per day for 14 days. The therapeutic effects were evaluated according to measurements of skin lesion severity (modified SCORAD score), transepidermal water loss (TEWL), serum IgE and inflammatory cytokine levels, lesion thickness measured after hematoxylin and eosin staining, and immunohistochemical and Western blot analysis for skin epidermal differentiation protein. RESULTS: The EOCO group exhibited significantly reduced modified SCORAD score, TEWL, and serum IgE levels. Among the inflammatory cytokines analyzed, only the mean values of regulated on activation, normal T cell expressed and secreted were observed to be decreased compared with other control groups. The histological analysis of the skin also revealed that the EOCO group expressed reduced epidermal hyperplasia and recovered filaggrin, involucrin, and loricrin expression. CONCLUSIONS: It was confirmed that fabric containing EOCO has anti-atopic and anti-inflammatory properties. The study data show that fabric containing EOCO can be implemented as an alternative functional clothing for people suffering from AD.


Assuntos
Anti-Inflamatórios/uso terapêutico , Chamaecyparis , Vestuário , Dermatite Atópica/terapia , Óleos Voláteis/uso terapêutico , Animais , Anti-Inflamatórios/farmacologia , Fibra de Algodão , Citocinas/sangue , Dermatite Atópica/sangue , Dermatite Atópica/metabolismo , Dermatite Atópica/patologia , Proteínas Filagrinas , Imunoglobulina E/sangue , Proteínas de Filamentos Intermediários/metabolismo , Masculino , Proteínas de Membrana/metabolismo , Camundongos , Óleos Voláteis/farmacologia , Fitoterapia , Precursores de Proteínas/metabolismo , Pele/efeitos dos fármacos , Pele/metabolismo , Pele/patologia
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