Medial and lateral discoid meniscus in the same knee.

To our knowledge, only 1 case of medial and lateral discoid meniscus in the same knee has been reported. We report on 2 cases of medial and lateral discoid meniscus in the same knee.

Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana.

The antioxidant activity of Artemisia montana was determined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and inhibitory activity against free radical generation of hepatocytes (AC2F). The methanol extract of A. montana showed strong radical scavenging activity at a concentration of 10.1 microg/ml, and thus fractionated by solvent extraction. Esculetin and luteolin 7-O-rutinoside (scolymoside) were isolated as the active principles from the EtOAc and Interphase fractions, respectively. The antioxidant activity of these compounds were comparable to that of L-ascorbic acid.

Tibial tuberosity avulsion fracture combined with meniscal tear.

Avulsion fractures of the tibial tuberosity are uncommon injuries. They usually occur during athletic activities in adolescents. The classification of these injuries has been divided into three types. Only two cases of avulsion fractures of tibial tuberosity have previously been reported with associated damages to menisci. We report a type III fracture of the tibial tuberosity associated with tear of the medial meniscus.

Minocycline for rheumatoid arthritis.

Minocycline may prove to be a valuable agent in adjunctive treatment of RA. The use of minocycline is attractive because of its relatively benign adverse effect profile in common dosages, although vestibular toxicity has occurred frequently when doses of 400 mg/d have been used. Adverse effects that do occur usually subside after discontinuation of the drug. Currently, the studies available offer no definitive conclusion concerning the use of tetracyclines for this purpose. These trials do show promise, however, and suggest that larger, controlled, double-blind studies with prolonged use of minocycline in patients are needed for confirmation of its efficacy in RA.

[Intestinal parasite and Clonorchis sinensis infection among the inhabitants in the upper stream of Taechong Dam, Kumgang (River)].

The prevalence of intestinal parasites and Clonorchis sinensis infection was observed among inhabitants in the upper stream of Kumgang (River) from January to October 1991. A total of 743 fecal specimens was examined by cellophane thick smear and formalin-ether concentration technique. The parasite positive rate including helminth eggs and protozoan cysts was 40.8%, the positive rates for every species were: Clonorchis sinensis 30.8%, Metagonimus spp. 14.5%, Fasciola spp. 0.7%, Taenia spp. 1.5%, Ascaris lumbricoides 0.4%, Enterobius vermicularis 0.1%, Hookworm 0.1%, Trichuris trichiura 1.6%, Entamoeba coli 0.7%, E. histolytica 0.3%, Endolimax nana 0.3%, Giardia lamblia 0.3% and Iodamoeba buetschlii 0.1%, respectively. The cumulative positive rate in Okchon-gun showed 51.1%, in the Kumsan-gun 50.8% and in the Muju-gun 28.6%. Through this survey, it was concluded that the soil transmitted intestinal parasites including helminthseggs and protozoan cysts have been decreased remarkably among the inhabitants along the upper stream of Taechong Dam, Kum-gang (River), on the other side, Clonorchis sinensis, Metagonimus spp. and Taenia spp. are still morderate prevalent.

[The characteristics of the lipid-hormonal interrelations in young men with a history of myocardial infarct (based on family registry data in Novosibirsk and Bishkek)]. / Osobennosti lipidno-gormonal'nykh vzaimosviazei u molodykh muzhchin, perenesshikh infarkt miokarda (po materialam semeinykh registrov v Novosibirske i Bishkeke).

Altogether 226 male probands who suffered large-focal or transmural myocardial infarction (MI) before reaching 50 years were examined in Novosibirsk and Bishkek in one stage according to the unified program. In Novosibirsk all the probands were Russians whereas in Bishkek 75 probands were Kirghizs and 71 were Russians. The probands were examined within a period of 1 to 3 years after MI. The lipid and lipoprotein plasma content was determined by standardized methods on a Tekhnikon AAP autoanalyzer. The content of thyroid hormones, insulin and cortisol was measured by means of RIA-kits and that of apolipoprotein B (ApoB) by radial immunodiffusion. It turned out that the patients from Novosibirsk demonstrated the highest content of cholesterol, low density lipoprotein cholesterol, the highest index of atherogenicity, the highest concentration of ApoB, and hyperinsulinemia. In the probands of both nationalities from Bishkek, the lipid spectrum did not differ substantially from the populational norm, the content of ApoB in the Russian probands was slightly lower than in those from Novosibirsk whereas in Kirghizs, the least content of thyroxin was recorded.

[The prevalence of the main risk factors among probands who have had a myocardial infarct at a young age and among their relatives (based on family registry data in Bishkek and Novosibirsk)]. / Rasprostranennost' osnovnykh faktorov riska sredi probandov, perenesshikh infarkt miokarda v molodom vozraste, i ikh rodstvennikov (po materialam semeinykh registrov v Bishkeke i Novosibirske).

Macrofocal or transmural myocardial infarction at the age under 50 in probands served the criterion for selection of 136 families in Bishkek and Novosibirsk (66 Kirghiz and 70 Russian families, respectively). Main risk factors in probands and their families were determined according to WHO methodological recommendations. Essential hypertension was more prevalent in probands and their families in Bishkek, while hypercholesterolemia was more common in Novosibirsk families. Smoking was documented in Bishkek and Novosibirsk probands in equal proportions, though there were more smokers among probands' sons in Bishkek. Overweight occurred with equal frequency in probands' wives and daughters in both cities, but in probands and their sons in Novosibirsk this risk factor appeared more prevalent. Novosibirsk cases of reduced levels of high-density lipoproteins cholesterol and triiodothyronine, elevated concentrations of apolipoprotein B and immunoreactive insulin outnumbered those in Bishkek.

[Possibility of correcting atherogenic dyslipoproteinemia by the mountain climate treatment]. / Issledovanie vozmozhnosti korrektsii aterogennykh dislipoproteinemii gornoklimaticheskim lecheniem.

Whether dyslipoproteinemias can be corrected with 24-day mountain therapy in a mid-mountainous area (the village of Malinovka, 1600 m above the sea-level) was studied in 225 males who had sustained large myocardial infarction. The posthospital rehabilitation of postinfarction patients in a mid-mountainous sanatorium caused a substantial change in blood lipoprotein composition, which were generally antiatherogenic. The antiatherogenic changes in blood lipoprotein composition retained within 10 months after their stay at the sanatorium, which indicates that mid-mountain climate is a promising tool for non-drug prevention and correction of atherogenic dyslipoproteinemias.

[Study of the effect of migration to high-mountain regions on the blood lipoprotein system]. / Issledovanie vliianiia migratsii v gornye regiony na sistemu lipoproteidov krovi.

The effect of regular migration of lowlands residents to highlands on their blood lipoproteins was investigated. As compared to non-migrants, the migrants showed a decrease of serum total cholesterol, a reduction of low density lipoproteins, and an increase of high density lipoproteins. The antiatherogenic changes in blood lipoproteins were correlated with a lower prevalence of ischemic heart disease in migrants.

[Study of the age dynamics of nutritional indicators and blood lipids in connection with the incidence of ischemic heart disease in the male population of Frunze]. / Izuchenie vozrastnoi dinamiki pokazatelei pitaniia i lipidov krovi v sviazi v rasprostranennost'iu ishemicheskoi bolezni serdtsa v populiatsii muzhchin g. Frunze.

Epidemiological investigation of males aged 20-59 years in Frunze has shown atherogenic tendency of age dynamics of blood lipid level. The character of the nutrition of the population studied proved to be as a whole atherogenic due to imbalance with respect to the main food substances. The shifts detected in the parameters of nutrition and blood lipids correlate well with rather high incidence of coronary heart disease among the population investigated.

[Blood lipid levels and the nature of the nutrition of 40- to 59-year-old men in the city of Frunze in relation to their ethnic classification]. / Issledovanie urovnia lipidov krovi i kharaktera pitaniia u muzhchin 40-59 let g. Frunze v zavisimosti ot étnicheskoi prinadlezhnosti.

The relationship between the nutrition character and blood lipid parameters was studied in a male population aged 40-59 years in Frunze. It was established that the levels of total cholesterol, low- and high-density lipoprotein cholesterol in the natives were lower, while those of triglycerides and very low-density lipoprotein cholesterol higher than in the nonnatives. At the same time the correlation values of atherogenic and antiatherogenic lipoproteins in the comparable groups were equally high. In spite of certain differences in the nutrition of the groups investigated (the percent of proteins and complex carbohydrates was higher, while the portion of simple carbohydrates and fat was lower in the ration of the natives than in the nonnatives) actual nutrition of both the native and nonnative populations is characterized by imbalance of certain groups of nutrients in the ration: prevalence of fats and low carbohydrate content.