RESUMO
Seventeen medicinal plants used popularly in Brazil for their reputed analgesic properties were tested in mice by the writhing and tail flick methods. All extractions were made in 50% aqueous ethanol at low temperatures. The oral dose administered was always 1 g extract/kg. Significant effects in both tests were produced by Lippia alba, Piper abutiloides, Piper cincinnatoris, Piper lindbergii and Tillandsia usneoides.
Assuntos
Analgésicos , Plantas Medicinais/análise , Animais , Brasil , Avaliação Pré-Clínica de Medicamentos , Feminino , Camundongos , Medição da Dor , Fenóis/análise , Extratos Vegetais/farmacologia , Tempo de Reação/efeitos dos fármacosRESUMO
Twelve medicinal plants used popularly for their reputed analgesic properties were tested in mice by the writhing and tail-flick methods. All extractions were made using 50% aqueous ethanol at low temperatures. The oral dose administered was always 1 g solids/kg. While several extracts showed a positive effect in one of the tests, significant effects in both tests were produced by Serjania communis only. Morphine and acetylsalicylic acid were used as reference drugs.