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1.
Br Dent J ; 228(12): 902, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32591675

Assuntos
Antivirais
2.
Br Dent J ; 228(9): 656-657, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32385428

Assuntos
Povidona-Iodo
3.
J Intensive Care Soc ; 21(1): 18-21, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32284713

RESUMO

Point-of-care ultrasound (POCUS) is the use of bedside ultrasonography by the treating clinician, incorporating those images into direct clinical decisions. While there are a number of different techniques and training pathways in this relatively new modality, there has been little discussion around the logistics of integrating POCUS into the standard critical care "business day" of ward rounds, procedures and meetings. This article explores some of these aspects and presents data from an online survey of POCUS practitioners.

4.
Br J Anaesth ; 114(4): 598-604, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25500941

RESUMO

BACKGROUND: Stroke volume variation (SVV) and pulse pressure variation (PPV), termed dynamic markers of preload responsiveness, may predict the response to i.v. fluid in critically ill patients. However, the predictive accuracy of these variables during gastrointestinal surgery remains uncertain. METHODS: Observational study of patients aged ≥50 yr undergoing major gastrointestinal surgery, enrolled in the OPTIMISE trial. Patients received six 250 ml fluid challenges with i.v. colloid solution (three during and three after surgery), while SVV and PPV were measured using the LiDCOrapid monitor (LiDCO Ltd, UK). Fluid responsiveness was defined as a stroke volume increase ≥10%. Area under the receiver operating characteristic curve was calculated with 95% confidence intervals. Adjustment for covariates was performed by regression modelling and a clustering method was used to adjust for intra-patient correlation. RESULTS: One hundred patients were recruited between August 2010 and October 2012. Five hundred and fifty-six fluid challenges were administered and 159 (28.6%) were associated with increased stroke volume. The predictive value of both variables was poor during surgery [SVV 0.69 (0.63-0.77); PPV 0.70 (0.62-0.77)], and also after surgery [SVV 0.69 (0.63-0.78); PPV 0.64 (0.56-0.73)]. The findings were similar when analysed according to whether patients were mechanically ventilated [SVV 0.68 (0.63-0.77); PPV 0.69 (0.61-0.77)] or breathing spontaneously [SVV 0.69 (0.61-0.77); PPV 0.63 (0.56-0.72)]. Predictive value improved slightly in a sensitivity analysis excluding outlier values of SVV and PPV. CONCLUSIONS: In this study, the predictive accuracy of SVV and PPV for fluid responsiveness was insufficient to recommend for routine clinical use during or after major gastrointestinal surgery.


Assuntos
Pressão Sanguínea , Procedimentos Cirúrgicos do Sistema Digestório , Hidratação , Volume Sistólico , Idoso , Idoso de 80 Anos ou mais , Feminino , Hidratação/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Curva ROC
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