1.
Eksp Onkol
; 12(1): 75-7, 1990.
Artigo
em Russo
| MEDLINE
| ID: mdl-2298150
RESUMO
The data on the photodamage of biomolecules and experimental tumours by a hematoporphyrin derivative activated with laser radiation are presented. Inhibition of the tumour growth and prolongation of the life-span of treated tumour-bearing animals are observed.
Assuntos
Fotorradiação com Hematoporfirina , Neoplasias Experimentais/tratamento farmacológico , Nucleotídeos/análise , Fotoquimioterapia , Animais , Feminino , Masculino , Camundongos , Camundongos Endogâmicos C3H , Camundongos Endogâmicos C57BL , Ratos , Ratos Endogâmicos
2.
Nauchnye Doki Vyss Shkoly Biol Nauki
; (5): 5-14, 1989.
Artigo
em Russo
| MEDLINE
| ID: mdl-2527567
RESUMO
The biological mechanisms of photodynamic therapy, a new approach to the treatment of malignant lesions, are considered. The data on chemical composition of hematoporphyrin derivative are given, the photophysical and photochemical reactions caused by photosensitizer distribution in organism and cell, as well mechanisms of photodestruction of cells and cell organelles.