[The prospective of using plant polyphenols as functional food ingredients].

In this review we briefly discuss the publications dedicated to experimental evaluation of hypoglycemic, hypolipidemic and antioxidant properties of different plant polyphenols. The stages of preclinical studies of their efficacy are presented: in silico studies with molecular docking methods and in vivo studies with the use of genetic and medicamental models of type 2 diabetes. The results of own studies present the substantiation of prospects of using the plant polyphenol extracts as functional food ingredients for diet therapy and treatment of patients with type 2 diabetes. It was shown using genetic fatty Zucker rats model that extract consumption led to lower blood glucose level, had beneficial effect on glucose sensitivity and also improved the reaction of insulin-sensitive tissues on exogenous injection of glucose and insulin. Hypoglycemic and hypolipidemic properties of bilberry leaves extract were characterized on male Wistar rats model of carbohydrate metabolism disorder (streptozotocin injection accompanied with consumption of 10% fructose solution). The results of previous studies showed the beneficial effects of bilberry leaves extract on carbohydrate metabolism and determined the task to enhance the efficacy of developed polyphenol ingredient by the way of sorption on protein food matrix - brown buckwheat flour. Thus, a brief review of presented in this article results of foreign and domestic experimental studies shows the prospect of using the individual plant polyphenols and polyphenol plant extracts as phytonutrients for diet therapy and treatment of diseases associated with disorders of carbohydrate and lipid metabolism.

[Promising source of micronutrients for specialized foods with modified carbohydrate profile: traditional medicine experience].

Worldwide experience of Traditional medicine (TM) has been successfully applied to the development of modern standardized herbal medicines. Mainly researchers are guided by local sources of medicinal plants and traditional medical systems. TM experience is also used in the search of plants considered as sources of biologically active substances (BAS) and food ingredients. The steady increase in the incidence of type 2 diabetes, makes clear the need for research of domestic plant sources of BAS (with a proven carbohydrate metabolism effect) to create modern specialized foods. This article proves the feasibility of using TM experience of Russia and some neighboring European countries (Belarus, Ukraine) to develop optimized compositions for specialized food products for patients with type 2 diabetes. For reliable identification of the most promising plants, 550 traditional antidiabetic herbal formulations of 66 traditional recipe directories were studied in Russia, Belarus and Ukraine. It revealed 37 species of plants included to more than 20% of all bibliographical sources, and 13 plants included to more than 50% of prescription directories. The 3 most popular are bilberry leaves, leaffruit of common bean, great nettle leaves.

[The role of the food industry in dietetic therapy of the population. Specialized confectionery diabetic food].

Diabetes mellitus is a serious health and social problem of modernity, which in the future will increase and experts predict that the number of patients in 2030 will exceed 438,4 million. Taking into account the seriousness of the problem, and the fact that diabetes hurts an increasing number of young adults, the problem of creating diabetic food products, the positive effect of which on the organism is confirmed by experimental and clinical studies, is very relevant. The overview briefly covers information about the role of diet and ways to modify the composition and formulations of confectionery products of industrial production. The results of industry work towards the development of diabetic confectionery products in Russian Federation and peculiarities of their production and implementation in the framework of the Customs Union countries are summarized. Monitoring of the information entered in the register of specialized food products has been carried out, the lack of common approaches and tools in regulation imposed on the diabetic products in Russia, Belarus and Kazakhstan has been revealed. The necessity of objective regulatory impact assessment has been established. Its results will form the basis of the development of a unified approach to the production, handling and identification of diabetic confectionery and of the introduction of the General principle in relation to the probative value of the data, confirming their quality and safety. To improve the quality of population life and to reduce losses from socially significant diseases is possible through the development of personalized diets and their filling with products with attractive sensory properties. These data indicate the need for training highly qualified specialists with interdisciplinary knowledge in the field of food technology, nutrition and medicine.