1.
Pharmazie
; 43(5): 344-6, 1988 May.
Artigo
em Alemão
| MEDLINE
| ID: mdl-3051055
RESUMO
Antiviral activity from anthracycline antibiotics of rhodomycin-type was investigated by two independent methods, which determined the infectious units and antigenity of incomplete virions. The action of rhodomycin was dependent on structure, number and position of amino sugar, which is in aglycon. The viruses of double-stranded DNA and RNA viruses was stronger inhibited as single-stranded RNA viruses. The antiviral activity were found to increase in the serial order iremycin less than adriamycin less than daunomycin less than alpha-rubicin I less than beta-rhodomycin I less than violamycin BI-complex by inhibition kinetic determined from Adeno virus.