RESUMO
The efficiency and safety of tablet drug Vitaprost in the treatment of 35 patients with chronic abacterial prostatitis associated with impaired spermatogenesis were evaluated. The treatment course comprises the use of drug 1 tablet 2 times a day for 60 days. It was shown that Vitaprost had a positive effect on the basic parameters of spermatogenesis, helping to increase the number of sperm cells (28.8%), their mobility (17%), and viability (14.2%). The number of abnormal sperm cells at the same time decreased by 26.2%.
Assuntos
Peptídeos/administração & dosagem , Peptídeos/metabolismo , Prostatite/tratamento farmacológico , Prostatite/metabolismo , Espermatogênese/efeitos dos fármacos , Adolescente , Adulto , Doença Crônica , Humanos , Masculino , Pessoa de Meia-Idade , Prostatite/patologia , Fatores de TempoRESUMO
Intracellular reorganization of secretory epitheliocytes in the main, intermediate, and periurethral prostatic glands was studied in chronic prostatitis under conditions of sexually-transmitted infections. The destructive and autophagic processes in the secretory epitheliocytes were stimulated by persistence of microorganisms, Mycoplasmataceae (mainly mycoplasmas and ureaplasmas) and Chlamydia trachomatis, in the prostatic terminal compartments, epithelial layer, and epitheliocytes. Significant intracellular reorganization of smooth-muscle cells was found: focal destruction of ultrastructures (mainly in the perinuclear zone) and lythic changes in the myofilaments (focal and diffuse).
Assuntos
Próstata/patologia , Prostatite/patologia , Infecções Sexualmente Transmissíveis/microbiologia , Infecções Sexualmente Transmissíveis/patologia , Adulto , Infecções por Chlamydia/microbiologia , Infecções por Chlamydia/patologia , Chlamydia trachomatis/isolamento & purificação , Humanos , Masculino , Infecções por Mycoplasma/microbiologia , Infecções por Mycoplasma/patologia , Mycoplasmataceae/isolamento & purificação , Miócitos de Músculo Liso/microbiologia , Miócitos de Músculo Liso/ultraestrutura , Próstata/microbiologia , Prostatite/microbiologiaRESUMO
The study is aimed at investigation of efficacy and safety of a combined effect of laser therapy and vibromagnetotherapy in complex treatment of patients with chronic urethroprostatitis in the presence of sexually transmitted infection (STI). A total of 35 males aged 20 to 51 years entered the study. They were divided into 3 groups. Group 1 received standard basic therapy, group 2 received basic and laser therapy, group 3 - basic treatment and laser plus vibromagnetotherapy. Effectiveness of the treatment was assessed by the evidence obtained from clinical, bacteriological, device and functional examinations. The results of the treatments were evaluated after 2 weeks of the follow-up. It is shown that patients of groups 2 and 3 achieved more pronounced improvement of clinical and laboratory indices, parameters of basal blood flow. Thus, physiotherapy, added to antibacterial treatment, is safe and effective in the treatment of chronic urethroprostatitis and STI.
Assuntos
Terapia a Laser/métodos , Magnetoterapia/métodos , Prostatite/terapia , Doenças Bacterianas Sexualmente Transmissíveis/terapia , Uretrite/terapia , Adulto , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Prostatite/complicações , Doenças Bacterianas Sexualmente Transmissíveis/complicações , Uretrite/complicaçõesRESUMO
Combined treatment of patients with chronic abacterial prostatitis and chronic pelvic pain syndrome including vibrothermomagnetic impacts on the perineum from the device AVIM-1 proved effective in relation to all aspects of the disease pathogenesis. The comfort and simple conduction of the procedures make the device use perspective not only in the treatment but also for prophylaxis of exacerbations.
