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1.
Hematol Rep ; 14(4): 305-309, 2022 Oct 10.
Artigo em Inglês | MEDLINE | ID: mdl-36278521

RESUMO

Sinus tumors are arduous to diagnose due to often prolonging asymptomatic course until the infiltration of the adjacent structures occurs. Therefore, patients are diagnosed with advanced-stage disease, which negatively affects the treatment outcomes. A 60-year-old male was referred to our ward from an outpatient clinic. The patient presented with double vision, right-side lacrimation, and exophthalmos. He also reported significant weight loss: 15 kg in 2 months. Physical examination revealed achiness and edema of the right temporal area, and subconjunctival hemorrhage of the right eye, and surprisingly no anosmia, no nasal obstruction, and no head/neck lymphadenopathy were present. The histopathology examination identified diffuse large B-cell lymphoma (CD20+ CD3- p63- bcl-2+ CD23-/+ bcl-6+ CD 10- MUM1+ Tdt- CD38- cyclin D1- CD30- c-myc+). The patient was qualified for R-CHOP immunochemotherapy (rituximab, cyclophosphamide, and hydroxydaunorubicin hydrochloride), which was well tolerated. After 3 months of treatment, all of the symptoms reversed and a whole-body PET scan showed no abnormal metabolic activity.

2.
Otolaryngol Pol ; 65(4): 289-92, 2011.
Artigo em Polonês | MEDLINE | ID: mdl-22000148

RESUMO

Küttner's tumor is a benign tumour-like lesion of the salivary glands. Predominantly affects the submandibular gland. It is also known as chronic sclerosing sialoadenitis or cirrhosis of submandibular gland. This is an underrecognized entity in the surgical pathology and cytology literature. Most patients experience recurrent pain, discharge and swelling that is often associated with eating, but others only have asymptomatic hard swelling of the submandibular gland. Histologic examination of the excised submandibular glands revealed preserved lobular architecture, thickening of interlobular septa by sclerotic tissue, dense lymphoplasmacytic infiltrate, preservation of ducts with periductal fibrosis, and variable loss of acini. The morphologic appearance, in conjunction with the elevated IgG4 expression, distinguishes chronic sclerosing sialadenitis from other inflammatory diseases of the salivary glands. Chronic sclerosing sialadenitis belongs to the spectrum of IgG4-related diseases. We present a case of Küttner's tumor in a 62-year-old female treated by surgery. Although this disease was first described by Küttner in 1896, this clinical entity which masquerades as carcinoma is underdiagnosed by many surgeons. There is not enough evidence to support any diagnostic means that could help in the differential diagnosis of this benign condition. Given the high rate of malignancy in firm, painless lesions of the submandibular gland, surgical excision is often advocated and Küttner's tumor is usually diagnosed by the histopathologist.


Assuntos
Ductos Salivares/patologia , Neoplasias das Glândulas Salivares/patologia , Sialadenite/patologia , Glândula Submandibular/patologia , Biópsia por Agulha Fina , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-Idade , Ductos Salivares/cirurgia , Neoplasias das Glândulas Salivares/cirurgia , Sialadenite/cirurgia , Glândula Submandibular/cirurgia
3.
Otolaryngol Pol ; 63(5): 403-6, 2009.
Artigo em Polonês | MEDLINE | ID: mdl-20169904

RESUMO

Diffusion tensor imaging is unique in its ability to non-invasively visualize white matter fiber tracts in the human brain in vivo. White matter fiber bundles of the human brain form a spatial defined by the anatomical and functional architecture. Determination of axonal pathways provides an invaluable means to study the connectivity of human brain and its functional network. Comparison of fiber tract properties across subjects requires comparison at corresponding anatomical locations. In this paper, we present application of white matter tractography method based on incoherent motion of water molecules in fiber tissue, mainly in central nervous system. This motion is itself dependent on the micro-structural environment that restricts the movement of the water molecules. In white matter fibers there is a pronounced directional dependence on diffusion. With white matter fiber tracking or tractography, projections among brain regions can be detected in the three-dimentional diffusion tensor dataset according to the directionality of the fibers. The authors indicate diagnostic possibilities of MR tractography in otolaryngology for imaging the nervous tracts of sense of hearing, smell and taste with particular consideration of otoneurological evaluation of patients with cochlear implants and bone anchored hearing aid (BAHA). White matter tracts can be evaluated independently by using diffusion tensor tractography, which appears to be a promising technique for determining changes in white matter in degenerative disease. The authors also indicate that method as a beneficial in the surgical planning for patients with intrinsic brain tumors.


Assuntos
Encefalopatias/diagnóstico por imagem , Encéfalo/diagnóstico por imagem , Imagem de Difusão por Ressonância Magnética/métodos , Vias Neurais/fisiologia , Tratos Piramidais/diagnóstico por imagem , Encéfalo/patologia , Encefalopatias/patologia , Mapeamento Encefálico , Difusão , Imagem de Difusão por Ressonância Magnética/instrumentação , Humanos , Processamento de Imagem Assistida por Computador/métodos , Imageamento Tridimensional , Tratos Piramidais/patologia , Radiografia
4.
Otolaryngol Pol ; 61(4): 399-403, 2007.
Artigo em Polonês | MEDLINE | ID: mdl-18260221

RESUMO

INTRODUCTION: Salivary gland neoplasms represent the diverse group of tumours encountered by the head and neck surgeons. MATERIAL AND METHODS: The study is analysis of 531 patients with parotid gland tumours in patients treated in ENT Department during 1986-2006. We analysed surgical treatment and intraoperative tumour stage. The results of histological diagnosis were presented. RESULTS: The frequency of incidence of benign neoplasm was 80%. The most frequent tumour was pleomorphic adenoma--75% and adenolymphoma--16%. Malignant tumours constituted 20% of all gland tumours. Mucoepidermoid (27%) and adenoid cyst (22%) carcinomas were the most common malignant tumour. Tumour stages T3-T4 was in 90%.


Assuntos
Adenocarcinoma/epidemiologia , Adenolinfoma/epidemiologia , Adenoma Pleomorfo/epidemiologia , Neoplasias Parotídeas/epidemiologia , Adenocarcinoma/patologia , Adenocarcinoma/cirurgia , Adenolinfoma/patologia , Adenolinfoma/cirurgia , Adenoma Pleomorfo/patologia , Adenoma Pleomorfo/cirurgia , Carcinoma Adenoide Cístico/epidemiologia , Carcinoma Adenoide Cístico/patologia , Carcinoma Adenoide Cístico/cirurgia , Carcinoma Mucoepidermoide/epidemiologia , Carcinoma Mucoepidermoide/patologia , Carcinoma Mucoepidermoide/cirurgia , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Neoplasias Parotídeas/patologia , Neoplasias Parotídeas/cirurgia , Polônia/epidemiologia , Estudos Retrospectivos
5.
Otolaryngol Pol ; 60(3): 377-83, 2006.
Artigo em Polonês | MEDLINE | ID: mdl-16989451

RESUMO

INTRODUCTION: In obliterative type of otosclerosis the stapes footplate is greatly thickened and diffusely replaced by a massive otosclerotic masses that fill in the oval window niche, often annular ligament cannot be visualized. In the case of obliterative otosclerosis the only effective way of treatment is surgery. MATERIAL AND METHODS: The analysed group consisted of 53 patients with primary obliterative otosclerosis. In the control group there were 30 consecutive patients treated for otosclerosis. The auditory organ was assessed on the ground of the following criteria for the frequencies 0.5, 1, 2 and 4 kHz.: 1. Change of pure tone thresholds of air conduction (AC) 2. Change of pure tone thresholds of bone conduction (BC) 3. Change of pure tone thresholds of air-bone gap (ABG) as the difference between the mean AC and BC thresholds before the operation (AC0 and BC0) and 12 months after the operation (AC1 and BC1). RESULTS: Postoperatively mean value of change of AC thresholds in the analysed group was about 24 +/- 2 dBHL and in the control group about 25 +/- 2 dBHL (no significant difference). In the analysed group the mean value of BC thresholds varied about 8 dBHL and in the control group about 11 dBHL (no significant difference). The average values of ABG after the operation varied about 14 +/- 1 dBHL in both--the analysed and the control group. Postoperatively the mean value ABG was amounted to 20 +/- 1 dBHL in the analysed group and in the control group to 18 +/- 1 dBHL (no significant difference). On the basis of the subjective assessment completely subsidence of aural tinnitus reported 70% patients in the analysed group and 80% patients in the control group. CONCLUSION: 1. The incidence of obliterative otosclerosis represents 9,6% of all otosclerotic patients treated surgically. 2. Stapedotomy is the treatment of choice in patients with obliterative otosclerosis, because significant improvement of AC, BC and ABG 12 months after the operation was reported, mean values did not differ between the above and control group. 3. Complete subsidence of aural tinnitus was reported in 70% patients with obliterative otosclerosis.


Assuntos
Audiometria de Tons Puros , Limiar Auditivo , Perda Auditiva Condutiva/diagnóstico , Otosclerose/cirurgia , Cirurgia do Estribo , Adulto , Feminino , Perda Auditiva Condutiva/etiologia , Testes Auditivos/métodos , Humanos , Pessoa de Meia-Idade , Otosclerose/complicações , Estudos Retrospectivos , Índice de Gravidade de Doença , Resultado do Tratamento
6.
Otolaryngol Pol ; 60(5): 653-61, 2006.
Artigo em Polonês | MEDLINE | ID: mdl-17263236

RESUMO

For many years otosclerosis has been an interesting otologic problem in regard to pathological and clinical aspects. Many various conceptions of otosclerosis development which finally lead to the stapes immobility in the oval window were discussed. Resent genetic studies indicate that genetic factors as a cause of otosclerosis possibly in combination with other factors localize 3 genes responsible for otosclerosis to chromosom 15q25q-q26, 7q34-36, 6p21-22. The aim of the study was audiometric evaluation of 1380 patients out of 1716 stapes operations performed in years 1973-2004. Audiometric assessment for air and bone conduction was performed according to the European Academy of Otology and Neuro-Otology (EAO-NO) criteria. Postoperative air-bone gap 11-20 dB for speech frequencies (500, 1000, 2000, 4000 Hz) was obtained in 64.8% and in 28.9% was less than 10 dB. Postoperative air-bone gap (11-20 dB) recognized as a good result is determined by factors such as preoperative hearing loss, onset and duration of the disease, advanced and multiple otosclerotic foci, patient's age etc. Actually postoperative air-bone gap shows the improvement of air and bone thresholds obtained post stapedotomy versus preoperative air bone gap. In previous years an "over-closure" effect was taken into consideration. Hearing improvement post stapes surgery which included the "over closure" effect was obviously better. The authors indicate the necessity of standardization of audiometric results post ear surgery.


Assuntos
Perda Auditiva Condutiva/cirurgia , Otosclerose/cirurgia , Janela do Vestíbulo/cirurgia , Mobilização do Estribo/métodos , Adolescente , Adulto , Idoso , Audiometria de Tons Puros , Limiar Auditivo , Condução Óssea , Criança , Feminino , Seguimentos , Perda Auditiva Condutiva/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Otosclerose/epidemiologia , Polônia/epidemiologia , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Prevenção Secundária , Mobilização do Estribo/estatística & dados numéricos , Resultado do Tratamento
7.
Pol Merkur Lekarski ; 19(111): 480-1, 2005 Sep.
Artigo em Polonês | MEDLINE | ID: mdl-16358918

RESUMO

Authors present audiometric results of 1200 patients with otosclerosis post stapedotomy. Air-conduction, bone-conduction and air-bone gap was measured prior the surgery and 12 months post stapedotomy for frequencies 0.5, 1.0, 2.0 and 3.0 kHz. In the analysed group of 1200 patients a postoperative air-bone gap 0-10 and 11-20 dB was obtained in 93.7% patients. The result of stapedotomy in reference to tinnitus based on the patients' subjective opinion showed that 78.0% patients were either free from tinnitus or tinnitus was subjectively decreased. Authors stress that some anatomical abnormalities in the tympanic cavity might influence on the result of stapes surgery.


Assuntos
Otosclerose/fisiopatologia , Otosclerose/cirurgia , Cirurgia do Estribo , Audiometria de Tons Puros , Condução Óssea , Humanos , Otosclerose/etiologia , Fatores de Tempo , Zumbido/etiologia , Zumbido/prevenção & controle , Resultado do Tratamento
8.
Otolaryngol Pol ; 59(2): 263-6, 2005.
Artigo em Polonês | MEDLINE | ID: mdl-16095099

RESUMO

One of the problems in the stapes surgery is the floating footplate. The frequency of incidence of this complication is 2% to 5.8% of all operations. The authors present the results of stapes operations in a group of 28 cases (2.5%) from all the 1120 operations, in which the surgeon experienced a floating footplate. The hearing results were evaluated on the base of the average gain of air-conduction thresholds and air-bone gap levels at 500, 1000, 2000 and 3000 Hz. The improvement of hearing we observed in 24 patients, 4 patients heard worse.


Assuntos
Estapédio/cirurgia , Cirurgia do Estribo/efeitos adversos , Adulto , Audiometria de Tons Puros , Limiar Auditivo , Condução Óssea , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
9.
Otolaryngol Pol ; 58(4): 817-20, 2004.
Artigo em Polonês | MEDLINE | ID: mdl-15603396

RESUMO

34 patients with otosclerosis operated at the ENT Clinic, were enrolled in this study. Prior and 4 months after stapedotomy the signal of DPOAE and the threshold levels for air and bone conduction were evaluated. No signal of otoacoustic emissions was registered in any of the patients prior stapedotomy. After operation DPOAE was registered in 23 out of 34 examined patients (67.6%).


Assuntos
Emissões Otoacústicas Espontâneas/fisiologia , Otosclerose/cirurgia , Cirurgia do Estribo , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
10.
Otolaryngol Pol ; 58(4): 831-7, 2004.
Artigo em Polonês | MEDLINE | ID: mdl-15603398

RESUMO

The aim of the study was evaluation of the hearing ability on the base of air conduction threshold at extended range of high frequencies in young subjects with primary arterial hypertension. Lack of internationally accepted reference value of air conduction hearing threshold at extended frequency range resulted in own evaluation of the audiometric zero point for air conduction at the range 8-18 kHz in "otologically healthy" subjects younger than 20 years. Detection of impaired hearing of the extended high frequencies range in young subjects with primary arterial hypertension may be useful in diagnostics of hypertension as well as in prophylactic examinations in the group of individuals with high risk of primary hypertension. Evaluation of air conduction threshold at extended frequency range allows to detect sensorineural hearing impairment undetectable with application of conventional frequency range.


Assuntos
Limiar Auditivo/fisiologia , Hipertensão/fisiopatologia , Adolescente , Adulto , Feminino , Humanos , Masculino
11.
Otolaryngol Pol ; 58(3): 529-33, 2004.
Artigo em Polonês | MEDLINE | ID: mdl-15311598

RESUMO

Since the publication of Miodonski, Zollner and Wullstein different methods and grafting materials have been promoted in tympanoplasty. The purpose of this study was to demonstrate the anatomical and functional results of tympanoplasty in comparison with the material used. The studies included a selected group of 142 patients who were operated on because of perforation of tympanic membrane. The analysed group consisted of 112 patients when perichondrium and cartilage were used to reconstruct the tympanic membrane. The comparison group consisted of 30 patients when fascia of the musculus temporalis was used to close a defect of the eardrum. In all cases before and after operation there was made tonal audiometry with indication for air and bone conduction within range from 500 to 4000 Hz, verbal audiometry after operation with indication of speech detection and speech reception threshold using mono-syllable NLA-93 test, tympanometry after operation and evaluation of anatomical results after surgery. The comparison of operation results showed that there was no significant difference between the two groups.


Assuntos
Cartilagem/transplante , Fáscia/transplante , Miringoplastia , Perfuração da Membrana Timpânica/cirurgia , Timpanoplastia , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Miringoplastia/métodos , Resultado do Tratamento , Timpanoplastia/métodos
12.
Otolaryngol Pol ; 58(1): 61-7, 2004.
Artigo em Polonês | MEDLINE | ID: mdl-15101261

RESUMO

This study reports the results of otosclerosis surgery performed during the past thirty years (1973-2002) in the ENT Clinic in Katowice. The authors present difficult anatomic relationships in the tympanic cavity which might have an influence on stapes surgery. Audiometric evaluation of 100 bilateral stapedotomies performed in 50 patients revealed that a small--hole stapedotomy is a safe technique and could be performed bilaterally. The group of 55 stapedotomies with stapedial tendon preserved was compared to the group of 55 stapedotomies with dissected tendon. SRT was better in the group where the tendon was preserved. In the group of 32 patients ABR before and after stapedotomy was recorded. The latency of V wave after the operation was reduced to the normal values what indicated a correct function of the ossicular chain postoperatively. In the group of 60 patients DPOAE prior and after stapedotomy was evaluated. Prior to the operation no signal of otoacoustic emission was registered, in 37 patients out of 60 the signal was present after the operation. DPOAE obtained postoperatively indicated successful ossicular chain restoration and inner ear function. Audiometric evaluation in reference to the group of 905 stapedotomies performed in years 1992-2001 showed that most of the patients were in group B--443/905 and C--402/905 according, in A group--60/905 according to Shambaugh. A-B gap < or = 10 dB was obtained in 469/905 (51.8%), the mean of the hearing threshold at 500, 1000, 2000 and 4000 Hz was 24.3 dB (+/- 8.3, med. 25.0) in A group and 32.0 dB in B and C group. The result of stapedotomy in reference to tinnitus based on the patients' subjective opinion. We may conclude that the key to the stapes surgery lies in the training and skillfulness of the surgeon using save small hole technique with stapedial tendon preservation to obtain the optimal physiologic function of the middle ear and to gain the best hearing results.


Assuntos
Cirurgia do Estribo/história , Adolescente , Adulto , Idoso , Criança , Feminino , Transtornos da Audição/diagnóstico , Transtornos da Audição/epidemiologia , Transtornos da Audição/história , Transtornos da Audição/cirurgia , História do Século XX , História do Século XXI , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença
13.
Otolaryngol Pol ; 57(3): 421-2, 2003.
Artigo em Polonês | MEDLINE | ID: mdl-14524188

RESUMO

Authors have described the case of 67 years women with an anterior midline neck tumor. The tumor was surgically excited and the microscope examination revealed thyroid tissue with colloid goiter. One must consider a midline ectopic thyroid gland in the differential diagnosis of masses in the neck.


Assuntos
Coristoma/cirurgia , Doenças da Glândula Tireoide/cirurgia , Glândula Tireoide/cirurgia , Idoso , Coristoma/patologia , Diagnóstico Diferencial , Feminino , Neoplasias de Cabeça e Pescoço/diagnóstico , Humanos , Cintilografia , Doenças da Glândula Tireoide/patologia , Glândula Tireoide/diagnóstico por imagem , Glândula Tireoide/patologia , Fatores de Tempo , Resultado do Tratamento
14.
Otolaryngol Pol ; 57(6): 889-92, 2003.
Artigo em Polonês | MEDLINE | ID: mdl-15049192

RESUMO

Since the publication of Miodonski, Zollner and Wullstein different methods and grafting materials have been promoted in tympanoplastic surgery. The purpose of this study was to demonstrate the anatomical and functional results of tympanoplastic surgery with the use of cartilage and perichondrium grafts. The studies included a selected group of 112 patients who were operated on because of perforation of tympanic membrane. The analysed group consisted of 112 patients when perichondrium and cartilage were used to reconstruct the tympanic membrane. In all cases before and after operation there was made tonal audiometry with indication for air and bone conduction within range from 500 to 4000 Hz, verbal audiometry after operation with indication of speech detection and speech reception threshold using mono-syllable NLA-93 test, tympanometry after operation and evaluation of anatomical results after surgery.


Assuntos
Cartilagem da Orelha/transplante , Miringoplastia , Perfuração da Membrana Timpânica/cirurgia , Timpanoplastia , Adolescente , Adulto , Idoso , Audiometria , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Miringoplastia/métodos , Transplante Autólogo , Resultado do Tratamento , Timpanoplastia/métodos
15.
Otolaryngol Pol ; 56(4): 489-91, 2002.
Artigo em Polonês | MEDLINE | ID: mdl-12378811

RESUMO

Authors described an extremely rare case of primary lipoma of the middle ear in 8-years old girl. A histological structure, localisation and occurrence of this tumor in the temporal bone was discussed on the basis of the literature. Authors have presented symptomatology, diagnosis difficulties and treatment of primary lipoma of the middle ear. They have paid attention to the course of disease and non-characteristic symptoms, which imitated the symptoms of the chronic otitis media.


Assuntos
Neoplasias da Orelha , Orelha Média , Lipoma , Criança , Diagnóstico Diferencial , Neoplasias da Orelha/patologia , Neoplasias da Orelha/cirurgia , Orelha Média/patologia , Orelha Média/cirurgia , Feminino , Humanos , Lipoma/patologia , Lipoma/cirurgia , Resultado do Tratamento
16.
Otolaryngol Pol ; 56(3): 345-52, 2002.
Artigo em Polonês | MEDLINE | ID: mdl-12162025

RESUMO

Study was carried out in frequency range 8-18 kHz with audiometer AS 10 HF. Lack of internationally accepted reference value of the hearing threshold of air conduction at extended frequency range resulted in own evaluation of the audiometric zero point for air conduction at the range 8-18 kHz in "otologically healthy" subjects younger than 20 years. They were divided into subgroup A and B according to age. Investigation of the threshold values for air conduction at extended range of high frequencies were base for evaluation of the audiometric zero value for the used equipment.


Assuntos
Audiometria de Tons Puros , Limiar Auditivo , Condução Óssea/fisiologia , Audição/fisiologia , Adolescente , Adulto , Audiometria de Tons Puros/instrumentação , Audiometria de Tons Puros/métodos , Estudos de Avaliação como Assunto , Feminino , Humanos , Masculino , Polônia , Valores de Referência , Fatores Sexuais
17.
Otolaryngol Pol ; 56(5): 629-31, 2002.
Artigo em Polonês | MEDLINE | ID: mdl-12523177

RESUMO

An extremely rare case of the 21 years women with the tuberculosis of the tympanic cavity behind the intact tympanic membrane was presented. The authors have described the clinical picture, diagnosis difficulties and ways of therapy. A surgical treatment and antituberculosis treatment was satisfactory.


Assuntos
Otite Média/diagnóstico , Otite Média/microbiologia , Tuberculose/diagnóstico , Adulto , Antituberculosos/uso terapêutico , Feminino , Humanos , Mycobacterium tuberculosis/isolamento & purificação , Otite Média/terapia , Tuberculose/terapia , Membrana Timpânica/cirurgia
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