[Treatment of hepatic insufficiency in benign mechanical jaundice].

The aim of this work was to estimate hepatic dysfunction and improve treatment of benign mechanical jaundice using an injection hepatoprotector. The study included 124 patients of whom 74 were given remaxol. 50 control subjects received basal therapy. The patients were randomized by the random sampling method. Severity of cholestasis was evaluated from the total and fractional bilirubin content and γ-glutamyl transpeptidase (GGT) level; AST and ALT activities were used to detect cytolysis. Liver synthetic function was estimated from prothrombin index (PTI) and coagulation function from fibrinogen level, PTI and APTT. Endogenous intoxication during biliary tract decompression was assessed by calculating the leukocyte intoxication index from the Kalf-Kalif formula. It was shown that remaxol suppresses cytolysis, reduces total and fractional bilirubin levels, improves bilirubin excretion in bile and decreases activity of hepatocyte excretory enzymes.

[Submucosal lipomas of the colon]. / Podslizistye lipomy obodochnoi kishki.

Seven patients with submucosal lipomas of the colon of various localization were treated at the clinic over 25 years. Planned operations were carried out on 4 and emergency operations on 3 patients for complications (obstruction of the intestine by a tumor and intestinal hemorrhage due to ulceration of the tumor extended from the mucosa). The variety of the clinical course allows the precise diagnosis to be made in rare cases only by means of colonoscopy and target biopsy. In a precisely established diagnosis, saving organ-preserving operations can be undertaken.