[Anthropometric measures of children in the period of clinical manifestation of celiac disease].

We have analyzed the data of children's physical development who have celiac disease. The purpose of the study is to analyze the interrelations of celiac patients' anthropometric data with the age of diagnostics and the disease duration. 186 children with morphologically verified celiac disease at the age of from 9 months to 16 years were included. It was shown that the patients of pre-preschool age have the deficiency of body weight much more often than the growth delay. As they grow older and when the disease duration increases first of all we meet with stunting, as the result a number of children with normal growth at school age decreases to 23, 3 %, and the frequency of somatogenic nanism exceeds 50%. We have revealed the negative correlation between the symptoms duration of the disease and the deviation of growth data. We have confirmed the point of view that the presence of strong deviations of data of physical development which children have is the indication for the screening for celiac disease.

[Lactose tolerance in children with chronic gastroduodenal zone diseases]. / Tolerantnost' k laktoze detei s khronicheskimi zabolevaniiami gastroduodenal'noi zony.

We determined the dependence of the frequency of lactose intolerance, particular features of the clinical presentation and laboratory showings on lactase deficiency on the basis of a complex clinical, anamnestic and laboratory study of 149 children with chronic gastroduodenal pathologies. It was established that the prevalence of lactose intolerance in children with superficial gastroduodenitis amounts to 58.8%, in children with erosive gastroduodenitis--66.7% and in children with stomach ulcers--83.3%. During the oral lactose load and a subsequent laboratory study we revealed an impairment of the hydrolytic function of small intestines accompanied by an increase of fecal excretion of carbohydrates (lactose and monosaccharides) as well as a considerable enhancement of bacterial fermentation. The detection of fecal excretion of the total glycoprotein hexoses characterizes a disorder of the morphofunctional state of the gastrointestinal tract in children with intestinal enzymopathies.

[Glycoprotein hexoses in feces of infants with lactose intolerance]. / Geksozy glikoproteinov v kale u detei rannego vozrasta s neperenosimost'iu laktozy.

A modified method for estimation of total glycoprotein hexoses in feces, based on their measurements in the blood serum, is presented. Sixty-six nursing children with lactose intolerance, breastfed or formula fed, were examined; formula fed babies were kept on mixtures with high and low lactose content. Glycoprotein hexose parameters were as follows (X +/- m): 13.51 +/- 1.93, 12.05 +/- 2.20, and 3.69 +/- 0.47 g/l feces. In control children without lactose intolerance (n = 33) this value was 3.6 +/- 0.79 g/l. Increased glycoprotein excretion is connected with glycocalix and small intestinal enterocyte alteration.