Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
2.
Environ Toxicol Chem ; 37(7): 1916-1925, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29663533

RESUMO

In the present study, we examined how sensitivity to oil changes in combination with environmental stressors in Fundulus grandis embryos. We exposed embryos (<24 h post fertilization) to a range of high-energy water accommodated fraction (HEWAF) concentrations (0-50 parts per billion [ppb] total polycyclic aromatic hydrocarbons [PAHs]) made from Macondo crude oil in conjunction with various environmental conditions (temperature: 20 and 30 °C; salinity: 3, 7, and 30 practical salinity units [PSU]; and dissolved oxygen: 2 and 6 mg/L). Endpoints included mortality, hatching rates, and expression of cytochrome p450 1a and 1c (cyp1a, cyp1c) in hatched larvae. There was 100% mortality for all fish under the 2 parts per million (ppm) dissolved oxygen regimes. For the 6 mg/L dissolved oxygen treatments, mortality and median lethal time (LT50) were generally higher in the 30 °C treatments versus the 20 °C treatments. Oil increased mortality in fish exposed to the highest concentration in the 20-3-6 (°C-PSU-mg/L), 25-7-6, and 30-30-6 conditions. Hatching was driven by environmental conditions, with oil exposure having a significant impact on hatching in only the 25-7-6 and 30-30-6 groups at the greatest HEWAF exposure. Expression of cyp1a was up-regulated in most treatment groups versus the controls, with cyp1c expression exhibiting a similar pattern. These data suggest interactive effects among temperature, salinity, and PAHs, highlighting a need to further assess the effects of oil exposure under various environmental conditions. Environ Toxicol Chem 2018;37:1916-1925. © 2018 SETAC.


Assuntos
Embrião não Mamífero/efeitos dos fármacos , Fundulidae/embriologia , Poluição por Petróleo , Petróleo/toxicidade , Estresse Fisiológico , Animais , Família 1 do Citocromo P450/genética , Família 1 do Citocromo P450/metabolismo , Embrião não Mamífero/metabolismo , Fundulidae/genética , Regulação Enzimológica da Expressão Gênica/efeitos dos fármacos , Larva/efeitos dos fármacos , Hidrocarbonetos Policíclicos Aromáticos/análise , Poluentes Químicos da Água/análise
3.
Phys Rev E ; 95(3-1): 032312, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28415303

RESUMO

We examine high-resolution urban infrastructure data using every pipe for the water distribution network (WDN) and sanitary sewer network (SSN) in a large Asian city (≈4 million residents) to explore the structure as well as the spatial and temporal evolution of these infrastructure networks. Network data were spatially disaggregated into multiple subnets to examine intracity topological differences for functional zones of the WDN and SSN, and time-stamped SSN data were examined to understand network evolution over several decades as the city expanded. Graphs were generated using a dual-mapping technique (Hierarchical Intersection Continuity Negotiation), which emphasizes the functional attributes of these networks. Network graphs for WDNs and SSNs are characterized by several network topological metrics, and a double Pareto (power-law) model approximates the node-degree distributions of both water infrastructure networks (WDN and SSN), across spatial and hierarchical scales relevant to urban settings, and throughout their temporal evolution over several decades. These results indicate that generic mechanisms govern the networks' evolution, similar to those of scale-free networks found in nature. Deviations from the general topological patterns are indicative of (1) incomplete establishment of network hierarchies and functional network evolution, (2) capacity for growth (expansion) or densification (e.g., in-fill), and (3) likely network vulnerabilities. We discuss the implications of our findings for the (re-)design of urban infrastructure networks to enhance their resilience to external and internal threats.

4.
Chemosphere ; 119: 948-952, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25303653

RESUMO

Silver nanoparticles (AgNPs) are being incorporated and are known to be released from various consumer products such as textiles. However, no data are available on the toxicity of AgNPs released from any of these commercial products. In this study, we quantified total silver released from socks into wash water by inductively coupled plasma mass spectrometry (ICP-MS) and determined the presence of AgNPs using transmission electron microscopy (TEM). We then exposed zebrafish (Danio rerio) embryos for 72 h to either this leachate ("sock-AgNP") or to the centrifugate ("spun-AgNP") free of AgNPs and compared their toxicity to that of ionic silver (Ag(+)). Our data suggest that AgNPs do get released into the wash water, and centrifugation eliminated AgNPs but did not decrease total silver concentrations, indicating that most of the silver in the sock-AgNP solution was in the ionic form. All embryos died during the first 24 h when exposed to undiluted sock-AgNP and spun-AgNP solutions resulting in significantly lower LC50 values (0.14 and 0.26 mg L(-1)) compared to AgNO3 (0.80 mg L(-1)). Similarly, at 72 hpf, both sock-derived solutions were more potent at affecting hatching and inducing abnormal development. These results suggest that both sock-AgNP and spun-AgNP solutions were more toxic than AgNO3. Previous studies have consistently shown the opposite, i.e., AgNPs are about 10 times less toxic that Ag(+). All together our results show that the high toxicity induced by the leachate of these socks is likely not caused by AgNPs or Ag(+). More studies are needed to evaluate the toxicity of the myriad of AgNP-coated commercial products that are now estimated to be close to 500.


Assuntos
Vestuário , Nanopartículas Metálicas/toxicidade , Prata/toxicidade , Poluentes Químicos da Água/toxicidade , Animais , Embrião não Mamífero/efeitos dos fármacos , Espectrometria de Massas , Nanopartículas Metálicas/ultraestrutura , Microscopia Eletrônica de Transmissão , Peixe-Zebra
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...