[Morphological substantiation for the surgical treatment of chronic hepatic abscess].

The results of histological investigation, conducted in 27 patients, operated on for chronic hepatic abscess, are presented. Macroscopic and microscopic characteristic of all zones of hepatic affection is adduced, the mechanisms of formation of pyogenic membrane, zones of infiltration and fibrosis in chronic hepatic abscess formation are delineated.

[Use of quantitative fluorescence polymerase chain reaction in the invasive prenatal diagnosis of Down's syndrome].

A quantitative fluorescence polymerase chain reaction (QF-PCR) technique based on the determination of triple-dose chromosome-specific short tandem repeats (STR) has been recently developed for the prenatal diagnosis of numeral abnormalities of chromosomes 21, 18, 13 and X and Y. This investigation examined 55 blood samples from healthy donors, 17 amniotic fluid samples, 27 blood samples from children with regular trisomy 21, 1 sample with a translocation variant of Down's syndrome, and 3 samples with triploidy. The heterozygosity of 4 STR markers specific for chromosome 21 was determined, which were used in QF-PCR to detect Down's syndrome.