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1.
Appl Radiat Isot ; 106: 145-50, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26249744

RESUMO

The reliability of Fricke gel dosimeters in form of layers for measurements aimed at the characterization of epithermal neutron beams has been studied. By means of dosimeters of different isotopic composition (standard, containing (10)B or prepared with heavy water) placed against the collimator exit, the spatial distribution of gamma and fast neutron doses and of thermal neutron fluence are attained. In order to investigate the accuracy of the results obtained with in-air measurements, suitable MC simulations have been developed and experimental measurements have been performed utilizing Fricke gel dosimeters, thermoluminescence detectors and activation foils. The studies were related to the epithermal beam designed for BNCT irradiations at the research reactor LVR-15 (Rez). The results of calculation and measurements have revealed good consistency of gamma dose and fast neutron 2D distributions obtained with gel dosimeters in form of layers. In contrast, noticeable modification of thermal neutron fluence is caused by the neutron moderation produced by the dosimeter material. Fricke gel dosimeters in thin cylinders, with diameter not greater than 3mm, have proved to give good results for thermal neutron profiling. For greater accuracy of all results, a better knowledge of the dependence of gel dosimeter sensitivity on radiation LET is needed.


Assuntos
Terapia por Captura de Nêutron/instrumentação , Dosagem Radioterapêutica , Modelos Teóricos , Método de Monte Carlo
2.
Radiat Prot Dosimetry ; 161(1-4): 422-7, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24435913

RESUMO

Gamma dose and thermal neutron fluence in a phantom exposed to an epithermal neutron beam for boron neutron capture therapy (BNCT) can be measured by means of a single thermoluminescence dosemeter (TLD-700). The method exploits the shape of the glow curve (GC) and requires the gamma-calibration GC (to obtain gamma dose) and the thermal-neutron-calibration GC (to obtain neutron fluence). The method is applicable for BNCT dosimetry in case of epithermal neutron beams from a reactor because, in most irradiation configurations, thermal neutrons give a not negligible contribution to the TLD-700 GC. The thermal neutron calibration is not simple, because of the impossibility of having thermal neutron fields without gamma contamination, but a calibration method is here proposed, strictly bound to the method itself of dose separation.


Assuntos
Terapia por Captura de Nêutron de Boro/métodos , Raios gama , Neoplasias/radioterapia , Dosimetria Termoluminescente/instrumentação , Dosimetria Termoluminescente/métodos , Calibragem , Fluoretos , Humanos , Compostos de Lítio , Nêutrons , Imagens de Fantasmas , Fótons , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador , Reprodutibilidade dos Testes
3.
Appl Radiat Isot ; 88: 118-24, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24345523

RESUMO

Suitable dosimeter methods have been proposed and tested, to measure the different dose contributions in small phantoms exposed to epithermal/thermal neutron beams designed for BNCT. One method is based on Fricke-gel dosimeter in small tubes of 2.8mm of external diameter, that allow determining profiles of gamma dose and of boron dose. The other method is based on the use of TLD-700 chips, from whose answer the contribution of thermal neutrons is subtracted by means of appropriate parameters of the glow curve.


Assuntos
Biomimética/instrumentação , Terapia por Captura de Nêutron de Boro/instrumentação , Radiometria/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Miniaturização , Dosagem Radioterapêutica , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
Appl Radiat Isot ; 70(7): 1313-6, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22138025

RESUMO

The LVR-15 research reactor's horizontal channel with its epithermal neutron beam is used mainly for boron neutron capture therapy. Neutrons from the reactor core pass through a special filter before the collimator and the beam outlet. Neutron fluence and spectrum are the basic characteristics of an epithermal neutron beam. Three methods used to measure the beam's neutron spectrum are described: the activation method, a Bonner sphere spectrometer with gold activation detectors and a Bonner sphere spectrometer with LiI(Eu) scintillation detector. Examples of results are compared and discussed.

5.
Appl Radiat Isot ; 69(12): 1911-4, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-21497100

RESUMO

Gamma and fast neutron dose spatial distributions have been measured at the collimator exit of the epithermal neutron beam of LVR-15 reactor (Rez). Measurements were performed by means of optically analyzed Fricke-gel-layer detectors. The separation of the two dose contributions has been achieved by suitable pixel-to-pixel elaboration of the light transmittance images of Fricke-gel-layer detectors prepared with water and heavy water.

6.
Appl Radiat Isot ; 68(4-5): 617-9, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20031426

RESUMO

Horizontal channel with epithermal neutron beam at the LVR-15 research reactor is used mainly for boron neutron capture therapy. Neutron fluence depth profiles in a water phantom characterise beam properties. The neutron fluence (approximated by reaction rates) depth profiles were measured with six different types of activation detectors. The profiles were determined for thermal, epithermal and fast neutrons.


Assuntos
Modelos Químicos , Reatores Nucleares , Água/química , Simulação por Computador , Nêutrons , Espalhamento de Radiação
7.
Appl Radiat Isot ; 67(7-8 Suppl): S202-5, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19375340

RESUMO

The epithermal neutron beam of the LVR-15 reactor provides the appropriate conditions for varied BNCT activity. The principal parameters have been frequently determined. The following detectors have been used for the measurement: set of activation monitors of different nuclides irradiated in free beam and in the water phantom, Si semiconductor detector with (6)LiF converter, twin ionization chambers, thermoluminescence dosimeters, gel dosimeters used for imaging of separate part of dose, neutron spectrometer of Bonner type. Obtained results of measured parameters are presented in the paper.


Assuntos
Terapia por Captura de Nêutron de Boro/instrumentação , Terapia por Captura de Nêutron de Boro/estatística & dados numéricos , Nêutrons Rápidos/uso terapêutico , Reatores Nucleares , Radiometria/estatística & dados numéricos , República Tcheca , Compostos Ferrosos , Géis , Humanos , Neoplasias/radioterapia , Imagens de Fantasmas/estatística & dados numéricos , Radiometria/instrumentação , Planejamento da Radioterapia Assistida por Computador/estatística & dados numéricos , Soluções , Dosimetria Termoluminescente/estatística & dados numéricos , Água
8.
Appl Radiat Isot ; 67(7-8 Suppl): S214-7, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19376722

RESUMO

A thorax phantom has been designed, consisting of PMMA and PE plates containing a cavity filled with a laboratory-made lung-substitute. Fricke-gel dosimeters have been placed in the lung-substitute volume, and the phantom has been irradiated at the epithermal column of LVR-15 reactor. Absorbed dose images have been obtained for both gamma radiation and charged particles emitted in the (10)B reactions with thermal neutrons. Measurements with thermoluminescence dosimeters (TLDs) and Monte Carlo (MC) calculations have been performed too, in order to attain inter-comparison of results.


Assuntos
Terapia por Captura de Nêutron de Boro/instrumentação , Terapia por Captura de Nêutron de Boro/estatística & dados numéricos , Nêutrons Rápidos/uso terapêutico , Neoplasias Pulmonares/radioterapia , Imagens de Fantasmas/estatística & dados numéricos , Planejamento da Radioterapia Assistida por Computador/estatística & dados numéricos , Boro/uso terapêutico , República Tcheca , Géis , Humanos , Isótopos/uso terapêutico , Reatores Nucleares , Fótons/uso terapêutico , Radiossensibilizantes/uso terapêutico , Radiometria/instrumentação , Radiometria/estatística & dados numéricos , Tórax
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