[The relation of physical work capacity to the arterial pressure level and risk factors for arterial hypertension]. / Sviaz' fizicheskoi rabotosposobnosti s urovnem arterial'nogo davleniia i faktorami riska arterial'noi gipertonii.

A multivariate regression analysis including muscular performance, arterial pressure, age, heart rate, body-weight index permitted identification of independent relations between pressure and muscular performance. The latter accounts for 3% variability in initial systolic pressure in females and for 3% variability in males under physical loading. Initial systolic pressure accounts for 5% variability of muscular performance in females. The dependence between muscular performance and diastolic pressure is indirect, noticeable only in physical load with the help of double product.

[Relationship of physical work capacity, blood pressure and other hypertension risk factors with the rate of erythrocyte Na/Li countertransport]. / Sviaz' fizicheskoi rabotosposobnosti, arterial'nogo davleniia i drugikh faktorov riska arterial'noi gipertenzii so skorost'iu Na/Li-protivotransporta éritrotsitov.

The relationship of physical working capacity (PWC), blood pressure and other arterial hypertension risk factors to the rate of red blood cell Na+/Li+ countertransport was examined in a representative sample comprising 60 individuals (22 males and 38 females) whose age was 35-54 years. Regression analyses demonstrated that there was no significant relationship between PWC and the rate of red blood cell Na+/Li+ countertransport, but a significant correlation was found between the rate of Na+/Li+ countertransport and "double product" (DP) as an indirect indicator of PWC and heart rate. Thus, there is a heart rate- and DP-mediated correlation between the rate of red blood cell Na+/Li+ countertransport and the level of PWC. The magnitude of a decrease in the rate of red blood cell Na+/Li+ countertransport depends inversely on the dynamics of heart rate in males and females and directly on the dynamics of DP in females. Hence, there is a direct relationship between the magnitude of a reduction in the rate of red blood cell Na+/Li+ countertransport and that of PWC increment during exercise.

[Blood pressure changes induced by various exercise regimes in patients with "mild" arterial hypertension]. / Dinamika AD pod vliianiem razlichnykh rezhimov fizicheskoi trenirovki u lits s "miagkoi" arterial'noi gipertenziei.

How two regimes of exercise training affect blood pressure changes was examined in 70 individuals with mild arterial hypertension. Prolonged controlled exercise training were shown to be an effective tool of non-drug correction of elevated blood pressure, the exercises aimed at developing aerobic tolerance being more beneficial. The magnitude of changes (increase) of working capacity may be an indicator for the effectiveness of exercise training programmes.

[Erythrocyte Na+/Li+ countertransport and arterial hypertension: data of a cross-sectional population study]. / Skorost' Na+/Li+-protivotransporta éritrotsitov i arterial'naia gipertoniia: dannye odnomomentnogo populiatsionnogo issledovaniia.

The relation of red blood cell Na+/Li+ countertransport rate to the prevalence of arterial hypertension (AH) and blood pressure was evaluated in 720 individuals aged 23-60 years. In all age groups, the rate of red blood cell Na+/Li+ countertransport was significantly higher in males than in females. Age, alcohol use, obesity in males and age, obesity, and Na+/Li+ countertransport rate in females are factors that predispose to AH, as evidenced by multivariate logistic analysis. The latter parameter is associated with obesity and diastolic blood pressure and unassociated with age, alcohol use, and smoke, as suggested by regression analysis. The distribution of Na+/Li+ countertransport rate values in the population after standardization for ruling out the impact of obesity is erroneous and shifted to the right. This allows it to be presented as a sum of two normal distributions. However, their analysis has failed to reveal statistically significant differences in blood pressure values of AH incidence. The rate of Na+/Li+ countertransport may be regarded as a biological population risk factor for AH, which is, however, less than such factors as age, obesity, and excessive alcohol use.

[Erythrocyte sodium-lithium countertransporter level as a risk factor of hypertension (prospective study data)]. / Velichina Na+/Li+ protivotransporta éritrotsitov kak faktor riska gipertonicheskoi bolezni (dannye prospektivnogo issledovaniia).

A 3-year prospective study was undertaken to evaluate the relation of red blood cell Na+/Li+ countertransport rates to the incidence of arterial hypertension. A total of 227 subjects (males and females aged 24-54 years)--a 20% representative sample of organized population--was followed up. The annual incidence of arterial hypertension was 4.3 among males and 2.7 among females. The baseline blood pressures and obesity in males and rates of Na+/Li+ countertransport in females were demonstrated to be factors associated with the incidence of arterial hypertension. The rate of red blood cell Na+/Li+ countertransport can be regarded as an independent biological risk factor for arterial hypertension.

[The role of the rate of sodium-lithium countertransport of the erythrocytes in arterial hypertension]. / O roli skorosti natrii-litievogo protivotransporta éritrotsitov pri arterial'noi gipertenzii.

The present work is concerned with the role of the velocity of Na+/Li(+)-countertransport of red blood cells (as an indicator of the function of cellular membranes) in the development of arterial hypertension under conditions of a populational study. A relationship is demonstrated between the velocity of Na+/Li(+)-countertransport and the sex, arterial pressure, body mass index, and blood serum triglycerides. The high velocity of Na+/Li(+)-countertransport is encountered in 25% of the population, being responsible for about 30% of all cases of arterial hypertension. Taking into consideration the modern multifactorial theory of the genesis of arterial hypertension, the high velocity of Na+/Li(+)-countertransport should be viewed as a definite disease pattern (one of several) and as a risk factor of arterial hypertension in women (the data of the prospective part of the study).

[The effect of different physical training regimens on the dynamics of arterial pressure and physical work capacity in persons with "mild" arterial hypertension]. / Vliianie razlichnykh rezhimov fizicheskoi trenirovki na dinamiku arterial'nogo davleniia i fizicheskoi rabotosposobnosti u lits s "miagkoi" arterial'noi gipertenziei.

The influence of three different modes of physical training (PT) on high arterial pressure was estimated in persons suffering from "mild" arterial hypertension. 154 men and women aged 35-54 years were entered into the study. In accordance with two different methods of estimating the initial physical work fitness (PWF), the test subjects were distributed into 4 groups. In these groups, the percentage of aerobic training aimed at the development of stamina was progressively raised. The dynamics of the initial PWF served as a criterion for the efficacy of PT. It has been demonstrated that firstly, both methods of estimating PWF are suitable enough for characterization of the dynamics of PWF, secondly, the decrease of arterial pressure is directly dependent on the effectiveness of the PT programs reflecting the dynamics of PWF, and, thirdly, PT aimed at the development of the general (aerobic) stamina is the most effective nonmedicamentous approach to the reduction of arterial hypertension.