1.
Exp Anim
; 51(5): 521-4, 2002 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12451716
RESUMO
The time-dependent effects of daily dosing of IGF-I (1.21 mg/g) on the linear growth of the femur were investigated in mice. The femoral length and volume and the number of osteoclasts were significantly greater after IGF-I injection as compared to the non-injected control, suggesting that the IGF-I imbalance might cause a quick turnover cycle of the bone resulting in the altered femoral modeling.