[Morphologic evaluation of coronary thrombosis in the course of recent myocardial infarction]. / Ocena morfologiczna zakrzepicy tetnic wiencowych w przebiegu swiezego zawalu miesnia serca.

Post-mortem studies of 50 cases of death in the course of recent myocardial infarction were made to analyse relations between coronary thrombosis and myocardial necrosis. We assessed and compared severity of necrotic changes in the myocardium in relation to thrombotic changes in the coronary vessels. Our results show an enhancement and evolution of thrombotic changes with time elapsing from the infarct completion and possible causal relations between a thrombus and infarct.

[Interdependence between hormonal disorders, stage of development and degree of malignancy of prostatic cancer. 1]. / L'interdépendance entre les troubles hormonaux, le stade d'évolution et le degré de malignité du cancer de la glande prostatique. Première partie.

The aim of this study was to determine whether in human clinical practice destruction of the prostate gland by a malignant process is accompanied by a fall in serum testosterone and dihydrotestosterone levels. Mean serum testosterone and dihydrotestosterone levels were significantly lower and LH levels notably higher in patients with metastases than in those without metastases. No notable differences were found between serum testosterone and dihydrotestosterone levels in relation to the degree of malignancy of the tumours. Concentrations of relatively inactive androgens (DHA and delta-4-androstenedione) in the serum were normal. The fall in serum concentration levels with later increase in LH levels is probably caused by malignant destruction of the prostate gland.

Histochemical investigation of aldosterone-secreting cells adenoma of the adrenal cortex.

Two cases of adenomas of adrenal cortex were examined. Both cases presented clinical symptoms of autonomic hyperaldosteronism. Histologically one adenoma had a benign structure, the other a malignant one. An ultrastructural and cytochemical assay of the benign form suggests that it is composed of so called "hybrid cells". Histochemically the cells of both adenomas were characterized by a 3-beta hydroxysteroid and succinic dehydrogenase reaction, the presence of MAO and nonspecific esterases and in some single cells 17-beta hydroxysteroid dehydrogenase.