Assuntos
Leucemia Mieloide Crônica Atípica BCR-ABL Negativa/diagnóstico , Biópsia , Medula Óssea/patologia , Humanos , Perfuração Intestinal/complicações , Perfuração Intestinal/cirurgia , Leucemia Mieloide Crônica Atípica BCR-ABL Negativa/complicações , Leucemia Mieloide Crônica Atípica BCR-ABL Negativa/etiologia , Leucemia Mieloide Crônica Atípica BCR-ABL Negativa/terapia , Masculino , Neoplasias , Peritonite/diagnóstico , Peritonite/etiologia , Peritonite/cirurgia , Adulto JovemRESUMO
OBJECTIVES: To evaluate if subcutaneous continuous glucose monitoring (sCGM) is feasible in cardiac surgery and if reliable glucose values are reported under hypothermic extracorporeal circulation. DESIGN: Feasibility trial. SETTING: University hospital. PARTICIPANTS: Ten consecutive patients undergoing coronary artery bypass grafting. INTERVENTIONS: Prior to surgery, during hypothermic extracorporeal bypass, and 48 hours postoperatively, arterial blood glucose samples were compared with sCGM every 30 minutes. Statistical analysis utilized Clarke's error grid and Bland-Altman plot. MEASUREMENTS AND MAIN RESULTS: Three hundred fifty-one pairs of glucose measurements were recorded including 59 during hypothermic extracorporeal circulation. Agreement between these measurements was acceptable, with a regression line slope of 0.88 and an offset of 17.4 (p = 0.87). Error grid analysis indicated a safe margin of 99.1% within zone A (no clinical action needed) or zone B (values would not lead to inappropriate treatment). Only 0.9% were plotted in zone D (potentially dangerous failure). Measurements during hypothermic extracorporeal circulation were comparable. Correlation coefficient was 0.760. The offset regression line was more pronounced (50.9) with a flatter slope (0.640). Within the error grid all plot values were in zone A or B. CONCLUSIONS: sCGM compared with arterial blood gas glucose monitoring under hypothermic extracorporeal circulation appears to be feasible and reliable.
