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Acta Pharm Hung ; 60(4): 121-9, 1990 Jul.
Artigo em Húngaro | MEDLINE | ID: mdl-2239339

RESUMO

Four materials of different properties in respect of compressibility, lactose, sodium chloride, microcrystalline cellulose (Avicel PH 101) and so-called simple granulate were investigated. In function of time and that of actual pressing force decrease of axial force on upper punch were measured in quasi-state. Evaluating relations it was established that both pressing time and pressing force had influence on deformation structural changes occurring inside compressed form. Furthermore, summing up of results showed that useful conclusions could be drawn from diagrams--which represented decrease of force--to compressibility properties of materials too.


Assuntos
Comprimidos , Celulose , Lactose , Pressão , Cloreto de Sódio
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