1.
Chem Commun (Camb)
; 51(54): 10957-60, 2015 Jul 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26063471
RESUMO
The photo-generated closed-ring isomer of bis(5-methyl-2-phenylthiazoyl)perfluorocyclopentene shows cytotoxicity to Madin-Darby canine kidney (MDCK) cells through a caspase cascade and induces apoptosis of cells.
Assuntos
Caspases/metabolismo , Ciclopentanos/química , Fluorocarbonos/química , Animais , Apoptose/efeitos dos fármacos , Apoptose/efeitos da radiação , Ciclopentanos/toxicidade , Cães , Fluorocarbonos/toxicidade , Isomerismo , Células Madin Darby de Rim Canino , Polímeros/química , Raios Ultravioleta
2.
Chem Commun (Camb)
; 51(9): 1736-8, 2015 Jan 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25519491
RESUMO
A closed-ring isomer of a diarylethene having a sulfone group works as the reagent for SO2 gas generation with thermal stability even at 70 °C, and it rapidly reverts to the open-ring isomer and generates the SO2 gas to induce cell death upon UV irradiation.