Sex differences in self-regulation in early, middle and late adolescence: A large-scale cross-sectional study.

This large-scale cross-sectional study had the aim to investigate whether adolescent males and females differ in self-perceived self-regulation. The large sample size allowed us to investigate sex differences in three age-groups of young (n = 161), middle (n = 133) and late (n = 159) adolescents. Self-regulation was evaluated with a self-report questionnaire, the Amsterdam Executive Functioning Inventory (AEFI). This questionnaire gives a proxi for three executive functions that are important for proper self-regulation: (1) self-control & self-monitoring, (2) attention, and (3) planning & initiative taking. Results revealed clear sex differences in the self-regulation as perceived by mid-adolescents (i.e., 13-16 years). In this age period, females evaluated their attention higher than males, and they reported higher levels of self-control & self-monitoring. Our findings offer important new insights with respect to the decision making, academic achievements and behaviour of 13-16-year olds. Self-regulation is known to have a central role in academic achievement and in behavioural organisation. The sex differences in self-regulation in mid-adolescence may therefore explain part of the difference which males and females in this age-group exhibit in academic achievements and behavioural organisations. The results imply that self-regulation may be a relevant intervention target: rather than focussing on changing behaviour, interventions may focus more on self-insights and thereby changing the adolescent's perceptions about their behaviour. Increased self-insight may have the potency to actually change behaviour, which might be an interesting target for future investigation.

Neuroscientific and behavioral genetic information in criminal cases in the Netherlands.

In this contribution an empirical approach is used to gain more insight into the relationship between neuroscience and criminal law. The focus is on case law in the Netherlands. Neuroscientific information and techniques have found their way into the courts of the Netherlands. Furthermore, following an Italian case in which a mentally ill offender received a penalty reduction in part because of a 'genetic vulnerability for impulsive aggression', the expectation was expressed that such 'genetic defenses' would appear in the Netherlands too. To assess how neuroscientific and behavioral genetic information are used in criminal justice practice in the Netherlands, we systematically collect Dutch criminal cases in which neuroscientific or behavioral genetic information is introduced. Data and case law examples are presented and discussed. Although cases are diverse, several themes appear, such as prefrontal brain damage in relation to criminal responsibility and recidivism risk, and divergent views of the implications of neurobiological knowledge about addiction for judging criminal responsibility. Whereas in the international 'neurolaw literature' the emphasis is often on imaging techniques, the Dutch findings also illustrate the role of neuropsychological methods in criminal cases. Finally, there appears to be a clear need of practice oriented instruments and guidelines.

Comparison of fibroglandular tissue distributions for microwave tomographic breast images with complementary MR T2 weighted images.

We have recently demonstrated good correlation between the recovered permittivity from microwave imaging (MIS) and the recovered water content from near infrared imaging (NIR) for a common set of normal patients undergoing associated breast examinations. We have subsequently conducted a small sample of comparison breast examinations between microwave imaging and MR to assess possible correlation between the location and extent of the fibroglandular as seen on MR images with increased permittivity zones of the microwave images. From various physiological and MR breast studies, it has been shown that the fibroglandular regions are generally comprised of significantly higher levels of water than the more dominant adipose tissue. The initial results of this study are quite encouraging and demonstrate obvious correlations between the permittivity and MR-recovered fibroglandular regions for a set of patients with widely varying tissue type variations. In addition, they illustrate the value of extracting diagnostic information from multiple modalities especially where the amount of direct in vivo property measurements is limited or nonexistent.

Deficits in social behavior in autism and their modification by a synthetic adrenocorticotrophic hormone (4-9) analog.

When charting the structure of the social behavior of autistic children by means of an ethologically analyzed playroom session, deficits appeared in the reciprocity of eye-contact and in the location of verbal initiatives. These deficits in social behavior were beneficially influenced by treatment with the adrenocorticotrophic hormone (4-9) analog ORG 2766.