1.
Biosci Biotechnol Biochem
; 76(10): 1979-81, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23047087
RESUMO
The epitopes for OVA323-339-specific CD4âºT cells from OVA23-3 food allergy model and DO11.10 tolerant induction model mice were analyzed. We found that OVA23-3 CD4âºT cells recognized the N-terminal region, showing strong proliferation and the Th2-phenotype, and that DO11.10 CD4âºT cells recognized the C-terminal region, showing milder proliferation and a Th1-skewed response. These differences may regulate the responses of those mice to OVA-feeding, inflammation and tolerance.