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1.
Rev. int. sci. méd. (Abidj.) ; 5(2): 114-121, 2023.
Artigo em Francês | AIM (África) | ID: biblio-1516844

RESUMO

Introduction. Au Mali, la prise en charge du paludisme se fait à travers la médecine conventionnelle et la médecine traditionnelle, mais peu d'évaluation existe sur les implications fi nancières de ces approches qui coexistent et qui sont pratiqués parfois de manière concomitante. L'objectif de cette étude était d'évaluer les coûts fi nanciers de ces deux approches du point de vue des patients. Méthodes. Ainsi, une étude transversale descriptive impliquant des patients ont été sélectionnés dans trois aires de santé et plus précisément dans des ménages, structures de santé conventionnelle et chez les praticiens de la médecine traditionnelle de Niono, Sirabala et N'Debougou. Des questionnaires structurés ont été utilisés pour collecter des informations. Le calcul du coût de traitement a été utilisé pour comparer le coût moyen de traitement du paludisme en médecine conventionnelle et traditionnelle. Résultats. Au total, 300 patients ont été sélectionnés. 52,7% des patients avaient recouru à la médecine conventionnelle, contre 32% pour l'automédication et 15,3% pour la médecine traditionnelle. Les patients avaient utilisé les ressources de ces trois systèmes de santé pour quatre principaux motifs. Le coût moyen du traitement par épisode de paludisme était estimé à 12,97 Euro en médecine conventionnelle contre 6,24 Euros en médecine traditionnelle. Le coût moyen du traitement de paludisme en automédication à base de médicaments conventionnels ou traditionnels était de 0,82 Euros. Conclusion. Dans notre étude, même si le coût du traitement du paludisme en médecine conventionnelle reste plus élevé que celui en médecine traditionnelle, contrairement aux idées reçues, les coûts des ressources de la médecine traditionnelle ne sont pas aussi bas qu'on le croit.


Introduction. In Mali, malaria management is done through conventional and traditional medicine, but little evaluation exists on the fi nancial implications of these approaches which coexist and are sometimes practiced concomitantly. The objective of this study was to evaluate the fi nancial costs of these two approaches from the patients' point of view. Methods. Thus, a descriptive cross-sectional study involving patients selected in three health areas and more precisely in households, conventional health structures and traditional medicine practitioners in Niono, Sirabala and N'Debougou. Structured questionnaires were used to collect information. The calculation of the cost of treatment was used to compare the average cost of treating malaria in conventional and traditional medicine. Results. Finally, 300 patients were selectionned and 52.7% of patients had used conventional medicine, compared to 32% for self-medication and 15.3% for traditional medicine. Patients had used the resources of these three health systems for four main reasons. The average cost of treatment per malaria episode was estimated at 12.97 Euros for conventional medicine versus 6.24 Euros for traditional medicine. The average cost of treatment of malaria by self-medication with conventional or traditional medicines was 0.82 Euros. Conclusion. In our study, even if the cost of treating malaria with conventional medicine remains higher than with traditional medicine, contrary to popular belief, the resource costs of traditional medicine are not as low as one might think


Assuntos
Humanos , Masculino , Feminino , Malária
2.
Mar Drugs ; 20(7)2022 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-35877734

RESUMO

Lipid peroxidation is associated with the development of some pathologies, such as cardiovascular diseases. Reduction in oxidative stress by antioxidants, such as Arthrospira (formely Spirulina), helps improving this redox imbalance. The aim of the study was to evaluate the effect of the Arthrospira liquid extract "Spirulysat®" on oxidative markers-in particular, oxidized LDL (oxLDL)/total LDL cholesterol-and isoprostanes and to investigate its impact on lipid and glucose metabolism in the metabolic syndrome subject. A controlled, randomised, double-blind design was conducted in 40 subjects aged 18 to 65 years with metabolic syndrome after a daily intake of Spirulysat® or placebo for twelve weeks. Blood and urinary samples were collected at three visits (V1, V2, V3) in the two groups for parameters determination. Although the Spirulysat® group showed a decrease at all visits of the oxLDL/total cholesterol ratio, there was no significant difference compared to the placebo (p = 0.36). The urinary isoprostanes concentration in the Spirulysat® group was reduced (p = 0.014) at V3. Plasma triglycerides decreased at V3 (p = 0.003) and HDL-cholesterol increased (p = 0.031) at all visits with Spirulysat®. In conclusion, Spirulysat® did not change the oxidized LDL (oxLDL)/LDL ratio but decreased the urinary isoprostanes, plasma triglycerides and increased HDL cholesterol, suggesting a beneficial effect on metabolic syndrome.


Assuntos
Síndrome Metabólica , Spirulina , Antioxidantes/farmacologia , Antioxidantes/uso terapêutico , Colesterol , HDL-Colesterol , Método Duplo-Cego , Humanos , Isoprostanos/farmacologia , Isoprostanos/uso terapêutico , Lipoproteínas LDL , Síndrome Metabólica/tratamento farmacológico , Estresse Oxidativo , Extratos Vegetais/farmacologia , Extratos Vegetais/uso terapêutico , Triglicerídeos
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