[Differences in the cognitive status of patients with schizophrenia depending on the genesis of concomitant encephalopathy]. / Razlichiya kognitivnogo statusa bol'nykh shizofreniei v zavisimosti ot geneza soputstvuyushchei entsefalopatii.

OBJECTIVE: To analyze the cognitive status of patients with schizophrenia and organic cerebral pathology of various genesis. MATERIAL AND METHODS: The study included 75 patients diagnosed with paranoid schizophrenia (F20.0). Depending on the type of organic brain lesion, all patients were divided into four groups: patients with paranoid schizophrenia without organic brain pathology (n=41), patients with dyscirculatory encephalopathy (n=15), patients with post-traumatic encephalopathy (n=12), patients with toxic encephalopathy (n=7).The Brief Assessment of Cognition in Schizophrenia (BACS) and the Rey-Osterrieth Complex Figure (ROCF) followed by the evaluation of the results with the Boston Qualitative Scoring System (BQSS)were used to assess the cognitive status. RESULTS AND CONCLUSION: Patients with schizophrenia without concomitant cerebral pathology had a better state of the cognitive sphere compared to patients whose underlying disease was aggravated by encephalopathy of various genesis. In particular, it applied to such cognitive functions as verbal memory, speech fluency, problem-solving behavior, long-term visual-motor memory, organization and constructive ability. According to the results of this study, patients with posttraumatic encephalopathy had the least pronounced cognitive deficit among patients with an organic brain lesion. In turn, patients with toxic encephalopathy had the worst indicators of the state of the cognitive sphere.

Comparative characterization of the skull bones after implantation of titanium biocomposites containing BMP-2 in their coating structure.

The skull bone tissue was studied under conditions of implantation of Grey nanostructured titanium containing biocomposites and bone morphogenetic protein-2 in the coating structure. Implantation of sandblast processed titanium led to more rapid formation of the bone tissue than the use of titanium biocomposites with microarch oxidation (due to porous surface). The type of metal processing was inessential for nanocomposites. Morphogenetic proteins stimulated regeneration and facilitated the formation of structures characteristic of the bone tissue.

[Impairments in the ultrastructure and macro- and microelement composition of hard tooth tissues in caries in patients with hypothyroidism and in those without thyroid disease].

Extracted teeth were studied in patients with hypothyroidism, by applying electron and atomic force microscopy. This method allows one to have extended morphometric characteristics. The patients with hypothyroidism were found to have superficial and internal changes in the enamel, dentin, and cement of intact and carious teeth. The macro- and microelement composition of teeth were investigated. In hypothyroidism, the resistance of dental tissue depends on the homogeneous structure of enamel and dentin.

Effect of thermal annealing in vacuum and in air on nanograin sizes in hard and superhard coatings Zr-Ti-Si-N.

Zr-Ti-Si-N coating had high thermal stability of phase composition and remained structure state under thermal annealing temperatures reached 1180 degrees C in vacuum and 830 degrees C in air. Effect of isochronous annealing on phase composition, structure, and stress state of Zr-Ti-Si-N-ion-plasma deposited coatings (nanocomposite coatings) was reported. Below 1000 degrees C annealing temperature in vacuum, changing of phase composition is determined by appearing of siliconitride crystallites (beta-Si3N4) with hexagonal crystalline lattice and by formation of ZrO2 oxide crystallites. Formation of the latter did not result in decay of solid solution (Zr, Ti)N but increased in it a specific content of Ti-component. Vacuum annealing increased sizes of solid solution nanocrystallites from (12 to 15) in as-deposited coatings to 25 nm after annealing temperature reached 1180 degrees C. One could also find macro- and microrelaxations, which were accompanied by formation of deformation defects, which values reached 15.5 vol.%. Under 530 degrees C annealing in vacuum or in air, nanocomposite coating hardness increased. When Ti and Si concentration increased and three phases nc-ZrN, (Zr, Ti)N-nc, and alpha-Si3N4 were formed, average hardness increased to 40.8 +/- 4 GPa. Annealing to 500 degrees C increased hardness and demonstrated lower spread in values H = 48 +/- 6 GPa and E = (456 +/- 78) GPa. Zr-Ti-Si-N coatings has high wear resistance and low friction coefficient in comparison at a temperature of 500 degrees C possess with coatings TiN, Ti-Si-N.