[The role of immunological mechanisms in the development of the late sequelae of nuclear disasters]. / O roli immunologicheskikh mekhanizmov v razvitii otdalennykh posledstvii iadernykh katastrof.

Effects, both specific and non-specific, were analysed of ionizing radiation in a comparative evaluation of medical sequels of the Chernobyl disaster and of the Semipalatinsk Range nuclear test. A hypothesis is advanced assuming that development of all major bodily morbid conditions is directly related to the dysfunction of certain complex of organs, the thyroid gland in the first place, the thymus gland known to be a central organ of systemic immunogenesis. A breach in the thymus link triggers harmful cascade reactions of neuroimmunoendocrinological regulation, appeared to be responsible for the pathogenesis of practically all pathologies disclosed.

[Characteristics of blood neutrophil reactions to acute hypoxia in mice of low and high tumor incidence strains]. / Osobennosti reaktsii neitrofilov krovi myshei nizko- i visokorakovykh linii na ostruiu gipoksiiu.

The dependence of the neutrophil reaction of the low-tumour strain mice CBA/CaLacY, BALB/cLacY and C57B1/6J on acute hypoxia upon the value of the initial activity (the Wilder-Leites rule is shown. This dependence is disturbed in the high-tumour strain mice AKR/JY and A/SnY. The possible presence of latent immunodeficiency in AKR/JY and A/SnY mice is discussed.

[Mechanism of the development of chronicity of pathologic processes in the North]. / O mekhanizme khronizatsii patologicheskikh protsessov na Severe.

Based on the analysis of morbidity and population's immunity status in the North, a conclusion has been drawn that changes in the immunological reactivity of the organism due to autosensitization form the basis for chronization of pathological processes in the Far North. The discussion of the problem is supported by the correlation of the findings with the material characterizing the infections developed in sensitization of the organism with other antigens (as exemplified by opisthorchiasis invasion). A hypothesis is made that chronic population stresses and mass-scale allergization of the population are causes of the recent global trend toward formation of chronic pathology.

[Effect of exposure to physical loading, hypoxia and hyperthermia on factors of the cellular anti-infection protection of the body]. / Vliianie vozdeistviia fizicheskoi nagruzki, gipoksii i gipertermii na faktory kletochnoi protivoinfektsionnoi zashchity organizma.

Examinations of 146 healthy males aged 20-25 years have shown that moderate exercise stimulates the function of peripheral macrophages. The same effect is produced by exercise in combination with a single exposure to hypoxia. On the contrary, combined exposure to exercise, hypoxia and hyperthermia leads to the development of a tendency towards the suppression of macrophagal phagocytosis. The functional loading of the body induces deep transformation of the structure of the correlative characteristics of phagocytosis and hemogram.